Objective
Antibiotics are currently being phased out of animal production but alternative methods are needed to combat bacterial diseases in food animals and to control transmission of pathogens responsible for food-borne illnesses to humans.
Potential alternatives a re few: Competitive Exclusion (CE) and Bacteriophage (phage) Therapy represent two of the most promising alternatives. Whilst there is one approved CE product on the market, commercial use is limited due to very high costs of production, highly restricted means of administration, and reduced efficacy. Phages are very specific in killing a limited range of bacterial strains, cf. antibiotics, and do not cause infections of animals or plants. Replication of a lytic phage results in lysis and killing of the host bacterium, increasing phage numbers considerably. Research has identified phages, which kill Salmonella, Campylobacter, and other pathogenic bacteria, and established rapid, simple methods for amplification of phages to very large numbers. Recent work has shown phages to be effective in removing contamination from poultry carcasses, and also in killing pathogens in the intestinal tract of live poultry and in eggs. Using this phenomenon to protect or cure infected animals is the focus of ongoing investigations.
This project will focus on trials in live poultry to evaluate the importance of the following factors on safety and quality (WP6): phage choice and production (WPs 2, 4); route of administration and timing of administration (WP5); quantity of phages administered (WP5); modelling of the infection and curing process (WP3). The project will also consider alternative strategies for potential constraints related with: development of phage-resistant strains of pathogens; mass application causing environmental concerns; destruction of phages by stomach acidity following oral administration.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences microbiology bacteriology
- natural sciences biological sciences microbiology virology
- engineering and technology other engineering and technologies food technology food safety
- medical and health sciences basic medicine pharmacology and pharmacy pharmaceutical drugs antibiotics
- agricultural sciences animal and dairy science domestic animals animal husbandry
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP6-2003-FOOD-2-A
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
BRAGA
Portugal
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.