Objective The MOTET project combines two major strategic tasks:1.) Transfer of expertise from the Nuclear Magnetic Resonance (NMR) centre in Frankfurt, currently one of the largest NMR facilities in Europe, to the newly installed National NMR centres at the University of Birmingham. Such transfer will allow the development of strong links between the two partners, including exchange of post-doctoral research fellows.2.) Task 1 will be integrated in a combined scientific project that develops novel technologies to study the key molecular processes involved in the formation of cancer.Two approaches will be pursued: Firstly, direct interactions between a protein involved in cancer formation and selected inhibitors (with potential chemo-preventive value) will be investigated using well-established biological and NMR technologies, of which Frankfurt is a world leader. Secondly, NMR-based metabolomics will be developed as a new technique to characterise the metabolic response of living cells to several protein inhibitors, in particular to assess their ability to halt cancer progression with minimal metabolic side effects. The combined research will necessitate the development of new NMR techniques and software for metabolic profiling. Fields of science natural sciencescomputer and information sciencessoftwarenatural sciencesbiological sciencesbiochemistrybiomoleculesproteinsnatural sciencesphysical sciencesopticsspectroscopyabsorption spectroscopymedical and health sciencesclinical medicineoncology Programme(s) FP6-MOBILITY - Human resources and Mobility in the specific programme for research, technological development and demonstration "Structuring the European Research Area" under the Sixth Framework Programme 2002-2006 Topic(s) MOBILITY-1.3 - Marie Curie Host Fellowships - Transfer of knowledge (TOK) MOBILITY-1.3.1 - Marie Curie Host Fellowships - Transfer of knowledge (TOK) - Development Scheme Call for proposal FP6-2002-MOBILITY-3 See other projects for this call Funding Scheme TOK - Marie Curie actions-Transfer of Knowledge Coordinator UNIVERSITY OF BIRMINGHAM EU contribution No data Address Edgbaston BIRMINGHAM United Kingdom See on map Links Website Opens in new window Total cost No data Participants (1) Sort alphabetically Sort by EU Contribution Expand all Collapse all JOHANN WOLFGANG GOETHE-UNIVERSITAT Germany EU contribution No data Address Senckenberganlage 31 FRANKFURT/MAIN See on map Links Website Opens in new window Total cost No data
