Obiettivo Microfluidic 'lab-on-a-chip' technology has revolutionized laboratory experimentation, thereby, demonstrating the potential of miniaturization, integration, and automatization to research-based industries.There is also a great need in the area of drug de sign and development to develop analytical techniques that require small amounts of material and which can analyze samples expeditiously and provide accurate measurement of physicochemical parameters. The proposed research is unique and innovative in that it combines state-of-the-art microfluidic and capillary electrophoresis (CE) separation techniques with molecular derivatization.Although CE on a microchip is relatively well-established the coupling of it to molecular derivatization reactions has only recently been examined and only in the Gomez laboratories. The chip electrophoresis technology needs mainly microfluidic and electromigration research.The applicant has a basic knowledge on both fields, however, he is not familiar in CE on a chip, and he cannot acquire this expertise in Hungary. At this time the best place to obtain this knowledge is in California (United States) in the labs of Professor Frank A. Gomez, where both chip electrophoresis technology and affinity CE can be studied.The applicant hopes to transfer the cutting-edge chip-CE technology from the United States to a less-favoured, eastern region of EU. The research will develop analytical techniques including design, preparation, and application of microfluidic devices and CE and will focus on examining molecules and enzymes involved in disease and public health.To create 'lab-on-a-chip' devices, manufacturing methods from the microchip industry were coupled to techniques involving fluid dynamics, analytical chemistry, and biochemistry resulting in miniature integrated biochemical processing systems. Hence, the proposed work described, herein, should be considered interdisciplinary and multidisciplinary in nature. Campo scientifico natural sciencesphysical sciencesclassical mechanicsfluid mechanicsmicrofluidicsnatural scienceschemical sciencesanalytical chemistryengineering and technologyother engineering and technologiesmicrotechnologylab on a chipnatural sciencesphysical sciencesclassical mechanicsfluid mechanicsfluid dynamicsnatural scienceschemical scienceselectrochemistryelectrophoresis Parole chiave affinity capillary electrophoresis capillary electrophoresis chip technology microfabrication microfluidic devices Programma(i) FP6-MOBILITY - Human resources and Mobility in the specific programme for research, technological development and demonstration "Structuring the European Research Area" under the Sixth Framework Programme 2002-2006 Argomento(i) MOBILITY-2.2 - Marie Curie Outgoing International Fellowships (OIF) Invito a presentare proposte FP6-2004-MOBILITY-6 Vedi altri progetti per questo bando Meccanismo di finanziamento OIF - Marie Curie actions-Outgoing International Fellowships Coordinatore UNIVERSITY OF DEBRECEN, SCHOOL OF INDEPENDENT FACULTIES Contributo UE Nessun dato Indirizzo Egyetem tér 1 DEBRECEN Ungheria Mostra sulla mappa Collegamenti Sito web Opens in new window Costo totale Nessun dato Partecipanti (1) Classifica in ordine alfabetico Classifica per Contributo UE Espandi tutto Riduci tutto CALIFORNIA STATE UNIVERSITY, LOS ANGELES Stati Uniti Contributo UE Nessun dato Indirizzo State University Drive 5151 LOS ANGELES, CALIFORNIA Mostra sulla mappa Collegamenti Sito web Opens in new window Costo totale Nessun dato