Objectif The growing notion that in the pathology of many human diseases immunity plays an important, sometimes determining, role and that the use of antibiotics results in resistant pathogens, make high demands upon immunology research. In the functional analysis of human diseases and the role of immunity therein mouse models are crucial. Progress in immunology would substantially accelerate by improving efficacy and success rate of the generation of genetically modified mice and their phenotypic analysis in the context of a coherent research network.Our proposal aims at:A platform of 4 laboratories with state-of-the-art technology and experience in the generation of mouse models surrounded by 8 research groups with state-of-the-art technology and experience in the phenotypic analysis of such mice and their application in human disease models. The goal is to provide multi-disciplinary training for a new generation researchers in both genetic modification of mice and analysis of their phenotype. This will enable the m to fulfil the increasing demands in immunology research. The training requires broad understanding at the level of molecules, cells, and whole organism. Researchers in this area need to have a broad understanding of the different research sub-areas, and acquire expertise in different disciplines from protein biochemistry through molecular and cell biology to the use of mice as model organisms. Our network has all expertise and offers broader and elaborate training than could be provided by any of the lab oratories alone.The additional input from the network ensures that potential research leaders with interests in immunology and human disease will get experience in multi-disciplinary approaches to specific biological questions. The network will offer an unique opportunity to young investigators to gain access to state-of-the-art technology and thinking in a wide variety of disciplines and systems as is not available within any one national context. Champ scientifique medical and health sciencesclinical medicinegastroenterologyinflammatory bowel diseasemedical and health sciencesmedical biotechnologygenetic engineeringmedical and health sciencesbasic medicineneurologymultiple sclerosismedical and health sciencesbasic medicineimmunologymedical and health scienceshealth sciencespublic healthepidemiologymodeling of diseases spread Mots‑clés Functional Genomics Programme(s) FP6-MOBILITY - Human resources and Mobility in the specific programme for research, technological development and demonstration "Structuring the European Research Area" under the Sixth Framework Programme 2002-2006 Thème(s) MOBILITY-1.1 - Marie Curie Research Training Networks (RTN) Appel à propositions FP6-2002-MOBILITY-1 Voir d’autres projets de cet appel Régime de financement RTN - Marie Curie actions-Research Training Networks Coordinateur AKADEMISCH ZIEKENHUIS LEIDEN Contribution de l’UE Aucune donnée Adresse Albinusdreef 2 PO Box 9600 LEIDEN Pays-Bas Voir sur la carte Liens Site web Opens in new window Coût total Aucune donnée Participants (8) Trier par ordre alphabétique Trier par contribution de l’UE Tout développer Tout réduire JOHANNES GUTENBERG-UNIVERSITäT MAINZ Allemagne Contribution de l’UE Aucune donnée Adresse Saarstrasse 21 PF 55099 MAINZ Voir sur la carte Liens Site web Opens in new window Coût total Aucune donnée IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY & MEDICINE Royaume-Uni Contribution de l’UE Aucune donnée Adresse Exhibition Road, South Kensington Campus PO Box 9600 LONDON Voir sur la carte Liens Site web Opens in new window Coût total Aucune donnée HELMHOLTZ-ZENTRUM FUER INFEKTIONSFORSCHUNG GMBH Allemagne Contribution de l’UE Aucune donnée Adresse Inhoffenstrasse 7 BRAUNSCHWEIG Voir sur la carte Liens Site web Opens in new window Coût total Aucune donnée EUROPEAN MOLECULAR BIOLOGY LABORATORY Allemagne Contribution de l’UE Aucune donnée Adresse Meyerhofstrasse 1 HEIDELBERG Voir sur la carte Liens Site web Opens in new window Coût total Aucune donnée INSTITUT FUER MOLEKULARE BIOTECHNOLOGIE GMBH Autriche Contribution de l’UE Aucune donnée Adresse Dr. Bohr-Gasse 3-5 PO Box 9600 VIENNA Voir sur la carte Liens Site web Opens in new window Coût total Aucune donnée THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD Royaume-Uni Contribution de l’UE Aucune donnée Adresse University Offices, Wellington Square PO Box 9600 OXFORD Voir sur la carte Liens Site web Opens in new window Coût total Aucune donnée UNIVERSITAET ZU KOELN Allemagne Contribution de l’UE Aucune donnée Adresse Albertus Magnus Platz 1 KOELN Voir sur la carte Liens Site web Opens in new window Coût total Aucune donnée UNIVERSITY COLLEGE LONDON Royaume-Uni Contribution de l’UE Aucune donnée Adresse Gower Street PO Box 9600 LONDON Voir sur la carte Liens Site web Opens in new window Coût total Aucune donnée