Objetivo We propose a theoretical study of dynamical aspects of molecular cell biology using techniques available from statistical physics, nonlinear dynamics and numerical simulation. As a complementary focus, we suggest independent studies on the dynamical critic al phenomena of stochastic systems.The objective is to develop appropriate theoretical techniques using standard models in a statistical physics framework, eg. dynamically growing interfaces, granular systems, etc. and then to utilise these well tested techniques on the target biological systems. Our major motivation is to study the dynamical properties of cytoskeletons, the filamentous protein network found in the cytoplasm of eukaryotic cells.The focus problems will be the dynamics of cilia and flagella , the hair like cellular appendages driven by molecular motors and the dynamics of cytoskeletal fibres during the non-equilibrium polymerisation of protofilaments and mitotic cell division. The flagellar dynamics has two-fold significance, that concerning the reproductive process through the fertilisation of an ovum by a sperm and the other concerning the hearing mechanism.Both processes are powered by molecular motors and are generally believed to be self-organising in nature. Utilising these fundamental symmetry principles and standard techniques from statistical and nonlinear physics, our goal is to develop a generalised theory which is able to reproduce the detailed dynamics by taking into account all relevant deterministic and stochastic contributions concerning flagellar motion.A closely related interest will be a study of the lung ventilation technique, a medical method to measure the lung volume of patients suffering from lung diseases. All theoretical predictions will frequently be cross-checked against experimental results available from leading laboratories. Ámbito científico natural sciencesphysical sciencestheoretical physicsparticle physicsnatural sciencesbiological sciencescell biologynatural scienceschemical sciencespolymer sciencesnatural sciencesphysical sciencesclassical mechanicsstatistical mechanicsengineering and technologyenvironmental engineeringenergy and fuelsenergy conversion Palabras clave Cytoskeletons field theory flagella numerical simulation renormalisation ventilation technique Programa(s) FP6-MOBILITY - Human resources and Mobility in the specific programme for research, technological development and demonstration "Structuring the European Research Area" under the Sixth Framework Programme 2002-2006 Tema(s) MOBILITY-2.3 - Marie Curie Incoming International Fellowships (IIF) Convocatoria de propuestas FP6-2002-MOBILITY-7 Consulte otros proyectos de esta convocatoria Régimen de financiación IIF - Marie Curie actions-Incoming International Fellowships Coordinador UNIVERSITA' DEGLI STUDI DI PADOVA,DIPARTIMENTO DI FISICA G. GALILEI Aportación de la UE Sin datos Dirección Via Marzolo 8 PADOVA Italia Ver en el mapa Enlaces Sitio web Opens in new window Coste total Sin datos
