Objectif The consortium will create innovative opportunities for the application of the novel technologies of three SMEs in the development of a new generation of anti-herpes-virus treatments. Herpesviruses cause some cancers and many human diseases varying from afflictions of moderate severity that none-the-less can cause extended morbidity, to serious infections that are life threatening. This is particularly true in immuno-compromised patients including transplant recipients and HIV-infected individuals, but even in healthy people herpes-viruses can cause serious problems, for example during childbirth. Congenital HCMV infection is a leading cause of birth defects, and HSV-2 infection necessitates birth by Caesarian section.At present the options for antiviral therapy are extremely limited, and, because of toxicity, the current anti-herpes drugs cannot be administered to pregnant women. There is a continuing need to develop alternative treatments because drug-resistant viruses are evolving. The technologies that are being developed by three SMEs in TargetHerpes will be applied in connection with the fundamental advances being made in Europe's leading herpes-virus research laboratories, to press forward the search for novel, effective treatments that can be used against a broad spectrum of herpes-virus diseases.The project will target different herpes-viruses at different stages of their infections in order to inhibit virus; entry, evasion of host defences, persistence in infected individuals, reactivation from latency. These objectives will be achieved by improving and using the reagents and methodologies of the SMEs, thus providing opportunities in product development and marketing, and a foundation for the SMEs in the commercial development of successful treatments and methodologies. In addition to these major benefits for the SMEs, TargetHerpes expects to make significant contributions to the LifeSciHealth goals of FP6 in combating major human diseases. Champ scientifique medical and health scienceshealth sciencesinfectious diseasesmedical and health sciencesclinical medicineclinical microbiology Programme(s) FP6-LIFESCIHEALTH - Life sciences, genomics and biotechnology for health: Thematic Priority 1 under the Focusing and Integrating Community Research programme 2002-2006. Thème(s) LSH-2005-1.1.0-3 - Topic for STREPs dedicated to SMEs in the area of Fundamental knowledge and basic tools for functional genomics in all organisms Appel à propositions FP6-2005-LIFESCIHEALTH-7 Voir d’autres projets de cet appel Régime de financement STREP - Specific Targeted Research Project Coordinateur ALMA MATER STUDIORUM - UNIVERSITÀ DI BOLOGNA. Contribution de l’UE Aucune donnée Adresse via Zamboni, 33 BOLOGNA Italie Voir sur la carte Liens Site web Opens in new window Coût total Aucune donnée Participants (8) Trier par ordre alphabétique Trier par contribution de l’UE Tout développer Tout réduire ARTTIC S.A. France Contribution de l’UE Aucune donnée Adresse 58A rue du Dessous des Berges PARIS Voir sur la carte Liens Site web Opens in new window Coût total Aucune donnée BIODEC S.R.L. Italie Contribution de l’UE Aucune donnée Adresse Via Calzavecchio, 20/2 CASALECCHIO DI RENO (BO) Voir sur la carte Liens Site web Opens in new window Coût total Aucune donnée FRIEDRICH-ALEXANDER UNIVERSITAET ERLANGEN-NUERNBERG Allemagne Contribution de l’UE Aucune donnée Adresse Schlossplatz 4 ERLANGEN Voir sur la carte Liens Site web Opens in new window Coût total Aucune donnée HEINRICH-HEINE-UNIVERSITAET DUESSELDORF Allemagne Contribution de l’UE Aucune donnée Adresse Moorenstrasse 5 DUESSELDORF Voir sur la carte Liens Site web Opens in new window Coût total Aucune donnée IBA GMBH Allemagne Contribution de l’UE Aucune donnée Adresse Rudolf-Wissell-Str. 28 GOETTINGEN Voir sur la carte Liens Site web Opens in new window Coût total Aucune donnée MEDICAL RESEARCH COUNCIL Royaume-Uni Contribution de l’UE Aucune donnée Adresse 20 PARK CRESCENT LONDON Voir sur la carte Liens Site web Opens in new window Coût total Aucune donnée PRIMM SRL Italie Contribution de l’UE Aucune donnée Adresse Via Olgettina, 58 MILAN Voir sur la carte Liens Site web Opens in new window Coût total Aucune donnée UNIVERSITY OF REGENSBURG Allemagne Contribution de l’UE Aucune donnée Adresse Universitaetsstrasse 31 REGENSBURG Voir sur la carte Liens Site web Opens in new window Coût total Aucune donnée