MAMMIProject reference: 37555
Funded under: FP6-LIFESCIHEALTH
Mammography with molecular imaging
Total cost:EUR 4 092 804
EU contribution:EUR 2 500 000
Topic(s):LSH-2005-2.2.0-9 - Improving resolution of current imaging devices relevant to cancer diagnosis and therapy
Call for proposal:FP6-2005-LIFESCIHEALTH-7
Funding scheme:STREP - Specific Targeted Research Project
The proposed project focuses on the development of a PET prototype dedicated to the examination of breast cancer, using a gamma ray sensor based on an innovative design and the new generation of photo-detectors and scintillating crystals. The innovative features of the PEMT (Positron Emission MammoTomography) system we propose will imply a high resolution (pushed to the physical limit), higher sensitivity and lower costs. It includes integrated analog and digital electronics through the design of an ASIC chip.
The main application will be early breast cancer diagnosis and evaluation of chemotherapy response. New radio-tracer molecules will be searched for the detection and visualization of the pharmacokinetics of breast tumours, more specific than glucose (FDG) for breast cancer, and based on human amino and fatty acids. Phase I Clinical trials will be performed with the new radio-tracers. A clinical multi-centric validation will be performed for the PEMT prototypes.