Objective
Affinity biosensors, due to their selectivity, sensitivity and the fact they can be developed in a reagent-less and reusable format, find large application in environmental and clinical analysis. Key elements in biosensor development are: (i) the electrode surface (transducer) chemistry/properties, (ii) the recognition element and (iii) the signal generation element. In this proposal electrodeposition of nano-particles will be investigated as a way of modifying the transducer (electrode) chemistry/properties in order to improve/optimise the performances/layout of electrochemical molecular beacon biosensor. Several applications of RnEs will be investigated. · RnEs as a possible route to improve biosensors sensitivity (due the intrinsic catalytic properties of the nano-particles) · RnEs as a way generating specific attachment sites suitable for the recognition element. · Nano-particles as physical masks (template) for patterning, at nano size level, self assembled monolayer (SAM) of thiolated molecules onto Au surface (definition free sites, suitable for the recognition element attachment, in an antifouling matrix). Furthermore the influences of nature of the redox centre over the performances of electrochemical molecular beacon will be investigated in this proposal. The knowledge generated will be applied to the realisation of electrochemical molecular beacon DNA sensors for the prenatal diagnosis of Cystic Fibrosis and Thalassemia two of the most common genetic diseases. These areas of application have been chosen because of the relevance of the two diseases and because of the necessity to simplify the pre natal diagnosis of them that currently is performed with invasive, costly and risky procedures such as amniocentesis and “chorionic villa sampling”.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
- engineering and technology electrical engineering, electronic engineering, information engineering electronic engineering sensors biosensors
- natural sciences biological sciences genetics DNA
- medical and health sciences clinical medicine obstetrics fetal medicine
- natural sciences chemical sciences catalysis
- engineering and technology nanotechnology nano-materials
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP7-PEOPLE-2007-2-1-IEF
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
43003 TARRAGONA
Spain
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.