Objective
The aim of this project is the design, fabrication and implementation of a microdevice able to synthesise radiopharmaceuticals for Positron Emission Tomography (PET) analysis, a technique usually employed in medicine for its unsurpassed sensitivity and specificity. We propose to develop a modular microfluidic architecture which can be used for standard synthesis protocols as well as for R&D of new radiopharmaceuticals. In order to achieve this target, emerging technologies in the field of micro reactors and micro total analysis systems (μ–TAS) have to be applied to the synthetic pathways typical for radiopharmaceuticals, thus improving the traditional approach in terms of efficiency and safety. A deep knowledge of the chemical processes and of the separation techniques involved in radiosynthesis is needed to define the features of the modules to be fabricated as well as state of art techniques in the field of micro fabrications and microfluidics for the implementation of high performance micro devices. Standard synthesis protocols and new radiopharmaceuticals will be carried into the micro devices thus evaluating their efficiency and versatility. The yields and the purity of the products produced into micro devices will be compared with those obtained with traditional methods and tested in vivo for Positron Emission Tomography (PET) analysis. To ensure the success of the overall project, we will take advantage of a strict collaboration between chemists, physics and engineers in an interdisciplinary approach. For this purpose, we built an international network collaboration between academic partners dealing with the technological side, an industrial partner for checking the system robustness and a physiological clinical institute able to evaluate the end-user outcome.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
- natural sciences physical sciences classical mechanics fluid mechanics microfluidics
- natural sciences chemical sciences nuclear chemistry radiochemistry
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP7-NMP-2007-SMALL-1
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
00185 Roma
Italy
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.