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Content archived on 2024-06-18

Multifunctional Photothermal Gold Nanoarrays for Cellular Manipulation

Objective

Transporting, organizing, attaching, guiding, releasing entities of various dimensions over different scales remain central to the development of high throughput biological devices able to conduct millions of tests in a short period of time. The proposed project intends to develop a new generation of substrates for cell manipulation based on photothermal processes. Specifically, it focuses on realizing standard and new functions related to tissue engineering and cell transportation by designing a single type of platform. This project aims to implement photothermal gold nanoparticle arrays (PGNAs) to physically manipulate various types of entities, like living cells. Each gold nanodot will play the role of an adhesive spot exposing the RGD peptide, which are separated by nonadhesive regions functionalized with poly(ethylene glycol) (PEG), so that cell-binding sites will exclusively interface the nanoparticle. By irradiating well-defined areas of the PGNAs with a focused laser beam, the fellow hopes to take advantage of the local heating generated by the nanoparticles to prevent cell attachment in these hot areas. This way, it is possible to study and integrate multiple functions in order to deliver one unique dynamic platform able to precisely control both cell adhesion (releasing, patterning, guiding) and cell transportation (via optofluidics) at the PGNA interface. The “Multi-PGNAs” project may permit to integrate the same nanotechnology for the development of modern applications, while providing innovative methodologies for designing new experiments in cell biology and nanophysics.

Fields of science (EuroSciVoc)

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Keywords

Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)

Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Call for proposal

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FP7-PEOPLE-2007-2-1-IEF
See other projects for this call

Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

MC-IEF - Intra-European Fellowships (IEF)

Coordinator

MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV
EU contribution
€ 162 096,91
Address
HOFGARTENSTRASSE 8
80539 MUNCHEN
Germany

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Region
Bayern Oberbayern München, Kreisfreie Stadt
Activity type
Research Organisations
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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

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