Swimming for reproduction (REPRO-SWIM): Identification of swimming induced metabolic and hormonal switches that trigger reproduction

Projektinformationen

REPRO-SWIM

ID Finanzhilfevereinbarung: 219971

Abgeschlossenes Projekt

Startdatum 1 Oktober 2008

Enddatum 30 September 2010

Finanziert unter

• Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013)

Gesamtkosten € 151 369,07

EU-Beitrag € 151 369,07

Koordiniert durch

UNIVERSITAT DE BARCELONA
Spain

Ziel

A long standing question in the reproductive physiology of fish is how the metabolic status determines the onset of sexual reproduction, which often coincides with the start of reproductive migration. We hypothesize that swimming in that case triggers metabolic and hormonal changes critical for the induction of maturation. Studies on migrant fish like eel and salmon support the hypothesis that swimming triggers sexual reproduction, mobilises energy reserves for fuel and positively influences gamete quality. The mechanism behind this is however non-elucidated. Exercise, such as performed by migratory species, can be used as an experimental factor in studying the interaction between the metabolic processes and the onset of sexual maturation. This knowledge is important in optimising aquaculture of commercially interesting species, taking rainbow trout as a model. This study will identify the key metabolic and hormonal factors and their expression profiles in the onset of sexual reproduction as induced by swimming. Using microarray technology, the transcriptional response to exercise of all important tissues involved - gonad, muscle, liver, fat, brain and pituitary - will be analysed in a holistic approach. The main genes involved in both reproductive and metabolic functions will be identified. The role of insulin-like growth factors, the most important candidates, will be established. The expression profile of the main identified genes will be confirmed by real time PCR. The function of the main regulated genes will be investigated in vivo by implanting zebrafish cells that express each of the selected genes. The career objective of the applicant is to acquire additional skills and expertise in becoming a multidisciplinary fish reproduction expert. In addition he would have insight in the role of swimming as natural reproductive trigger. The host and collaborators have an excellent scientific status and are capable to support this project.

Wissenschaftliches Gebiet

• agricultural sciences › agriculture, forestry, and fisheries › fisheries
• medical and health sciences › basic medicine › physiology
• engineering and technology › environmental engineering › energy and fuels

Schlüsselbegriffe

• Animal endocrinology
• Animal physiology
• Animal reproduction
• Aquaculture
• Biological sciences
• Natural sciences
• Zoology

Programm/Programme

• FP7-PEOPLE - Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013)

Thema/Themen

• PEOPLE-2007-2-1.IEF - Marie Curie Action: "Intra-European Fellowships for Career Development"

Aufforderung zur Vorschlagseinreichung

FP7-PEOPLE-2007-2-1-IEF
Andere Projekte für diesen Aufruf anzeigen

Finanzierungsplan

MC-IEF - Intra-European Fellowships (IEF)

Koordinator

UNIVERSITAT DE BARCELONA

Kontakt Verwaltung

Josep Planas (Dr.)

• EU-Beitrag: € 151 369,07
• Adresse: GRAN VIA DE LES CORTS CATALANES 585 ; 08007 Barcelona ; Spanien
• Region: Este › Cataluña › Barcelona
• Aktivitätstyp: Higher or Secondary Education Establishments
• Gesamtkosten: Keine Daten