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Content archived on 2024-06-18

Neuron-Glia Interactions in Nerve Development and Disease

Objective

The characteristic appearance of white matter in the nervous system results from a remarkable cellular structure called myelin. This membraneous sheath is wrapped around axons by dedicated glial cells, thereby allowing the rapid propagation of impulses along the axons. The importance of the myelin sheath is underscored by the many neurological diseases that are caused by loss or destabilization of the myelin sheath, such as multiple sclerosis, leukodystrophies and peripheral neuropathies. The formation and maintenance of myelin by Schwann cells and oligodendrocytes results from close interactions between the neuron and glia cell. However, despite the vast importance of myelin to the normal physiological function of the nervous system, the molecular mechanisms underlying axon-glial communication in health and disease still remains largely unknown. In this collaborative project we aim to unravel these molecular mechanisms, discover novel molecules involved in neuron-glia communication and identify and test new targets for pharmaceutical intervention to aid the regenerative capacity of the nervous system.

Fields of science (EuroSciVoc)

CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.

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Keywords

Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)

Programme(s)

Multi-annual funding programmes that define the EU’s priorities for research and innovation.

Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

FP7-HEALTH-2007-A
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Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

CP-FP - Small or medium-scale focused research project

Coordinator

ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM
EU contribution
€ 605 300,00
Address
DR MOLEWATERPLEIN 40
3015 GD Rotterdam
Netherlands

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Activity type
Higher or Secondary Education Establishments
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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

No data

Participants (7)

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