Objective The nature of the bonding environment and electronic state of Fe Atoms in the process of DNA strand scissioning by systems antibiotic Fe II, III would be investigated by 57 Fe Mossbaueur spectroscopy. The structure of complexes Fe-drug (-adriamycin,-bleomycin, et al.) as well as of model compounds and systems (such as Fe II,III complexes with nucleir acid constituents), would be also studied, preferably in solution phase, in order to possibly better understand and discuss the role of the metal in the scissioning. Fields of science natural sciencesbiological sciencesbiochemistrybiomoleculesnucleic acidsnatural sciencesbiological sciencesgeneticsDNAnatural sciencesphysical sciencesopticsspectroscopy Programme(s) FP1-STIMULATION 1C - Plan (EEC) to stimulate European scientific and technical cooperation and interchange, 1985-1988 Topic(s) Data not available Call for proposal Data not available Funding Scheme CSC - Cost-sharing contracts Coordinator Università degli Studi di Palermo EU contribution No data Address Via Archirafi 26-28 90123 Palermo Italy See on map Total cost No data Participants (2) Sort alphabetically Sort by EU Contribution Expand all Collapse all Medizinische Universität zu Lübeck Germany EU contribution No data Address Ratzeburger Allee 160 23562 Lübeck See on map Total cost No data Università degli Studi di Padova Italy EU contribution No data Address Via Marzolo 1 35131 Padova See on map Total cost No data