Objetivo Materials with nanometre-scale dimensions have unique functional properties that can lead to novel engineering systems with highly useful characteristics. Most traditional approaches to synthesis of nanoscale materials, unlike those in biology, require stringent conditions and often produce toxic byproducts. Within biology itself, biomaterials are highly organized from the molecular to the nanoscale, with intricate architectures that allow for optimum functionality. The focus for this proposal on bio-inspired materials is two-fold. In the first instance I aim to rationally design biologically responsive peptides to control the assembly and dis-assembly of bio-inorganic nanostructures and develop fundamental enabling technologies with applications in bio-sensing. The second focus is on exploiting our understanding of the natural biological nanostructures found in the complex extracellular matrix of tissues in order to engineer synthetic biomimetic nanostructures for improved cell growth and tissue regeneration. Outcomes will include greater fundamental understanding of cell-matrix interactions and cell differentiation as well as longer-term clinical impacts. I have begun to establish a creative research team with many developing international links and a record of timely high quality research. If successful with this proposal I will be able to manage my group to its full potential and to expand its influence and vision. The proposed research involves development of important new international collaborations in the basic sciences and is highly multidisciplinary in nature encompassing elements of engineering, biology, chemistry and physics and ranging from high-resolution techniques of surface analysis to peptide design and cell biology. Ámbito científico engineering and technologyenvironmental biotechnologybiosensingnatural sciencesbiological sciencesbiochemistrybiomoleculesnatural sciencesbiological sciencescell biologyengineering and technologyindustrial biotechnologybiomaterials Palabras clave biosensors tissue engineering Programa(s) FP7-IDEAS-ERC - Specific programme: "Ideas" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013) Tema(s) ERC-SG-PE6 - ERC Starting Grant - Computer science and informatics Convocatoria de propuestas ERC-2007-StG Consulte otros proyectos de esta convocatoria Régimen de financiación ERC-SG - ERC Starting Grant Institución de acogida IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE Aportación de la UE € 1 643 021,00 Dirección SOUTH KENSINGTON CAMPUS EXHIBITION ROAD SW7 2AZ LONDON Reino Unido Ver en el mapa Región London Inner London — West Westminster Tipo de actividad Higher or Secondary Education Establishments Investigador principal Molly Morag Stevens (Dr.) Contacto administrativo Shaun Power (Mr.) Enlaces Contactar con la organización Opens in new window Sitio web Opens in new window Coste total Sin datos Beneficiarios (1) Ordenar alfabéticamente Ordenar por aportación de la UE Ampliar todo Contraer todo IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE Reino Unido Aportación de la UE € 1 643 021,00 Dirección SOUTH KENSINGTON CAMPUS EXHIBITION ROAD SW7 2AZ LONDON Ver en el mapa Región London Inner London — West Westminster Tipo de actividad Higher or Secondary Education Establishments Investigador principal Molly Morag Stevens (Dr.) Contacto administrativo Shaun Power (Mr.) Enlaces Contactar con la organización Opens in new window Sitio web Opens in new window Coste total Sin datos