Cel DIA-ChIP seeks to develop state-of-the-art molecular techniques for the routine high-throughput analysis of clinical samples for advanced molecular diagnosis and biomedical research. This will be achieved through a collaborative partnership between academic, SME and public health partners interacting through the IAPP, and the secondments and recruitments it supports. New molecular diagnostics in clinical pathology need to be robust, cost effective and offer significant advantages over existing techniques. With the move towards personalised medicine the specificity of diagnosis will need to be enhanced significantly, yet in the short to medium term will need to be compatible with current gold standards of analysis. In this project the focus will be on the most important cancer affecting the female European population – Breast Cancer. The ability to analyse archived clinical material is currently limited to immuno-histochemistry and quantification the native biomolecules (DNA, RNA, protein). The advent of functional characterisation of these molecules i.e. DNA-protein interactions and DNA status will provide information to enhance diagnostic histopathology. Application to archival material will provide access to a hugely valuable resource and will contribute significantly to scientific understanding of disease processes by allowing the examination of large patient cohorts, and by facilitating direct comparison to model systems. Also by examining patient samples in concert with model human cell culture systems, alternatives to animal model systems will be developed. DIA-ChIP features the creation of a strategic partnership between 4 groups that is critical in realising the project. The partners will develop strong long-term collaborative links for future research projects and intellectual exchange that will serve to strengthen each of the partners positions. The ultimate aim is to ensure long-term co-operation between all sectors -Business, Academic, Public Health Dziedzina nauki medical and health scienceshealth sciencespublic healthnatural sciencesbiological sciencesgeneticsDNAmedical and health sciencesclinical medicineoncologybreast cancermedical and health sciencesbasic medicinepathologymedical and health scienceshealth sciencespersonalized medicine Słowa kluczowe biomarkers breast cancer cinical diagnosis epigenetics high-throughput screening transcription factors Program(-y) FP7-PEOPLE - Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013) Temat(-y) PEOPLE-2007-3-1-IAPP - Marie Curie Action: "Industry-Academia Partnerships and Pathways" Zaproszenie do składania wniosków FP7-PEOPLE-2007-3-1-IAPP Zobacz inne projekty w ramach tego zaproszenia System finansowania MC-IAPP - Industry-Academia Partnerships and Pathways (IAPP) Koordynator SWANSEA UNIVERSITY Wkład UE € 297 575,00 Adres SINGLETON PARK SA2 8PP Swansea Zjednoczone Królestwo Zobacz na mapie Region Wales West Wales and The Valleys Swansea Rodzaj działalności Higher or Secondary Education Establishments Kontakt administracyjny Julie Williams (Ms.) Linki Kontakt z organizacją Opens in new window Strona internetowa Opens in new window Koszt całkowity Brak danych Uczestnicy (4) Sortuj alfabetycznie Sortuj według wkładu UE Rozwiń wszystko Zwiń wszystko Active Motif S.A. Belgia Wkład UE € 380 620,00 Adres Avenue Franklin Roosevelt 104 bte 25 1330 Rixensart Zobacz na mapie Rodzaj działalności Private for-profit entities (excluding Higher or Secondary Education Establishments) Kontakt administracyjny John Heyman (Dr.) Linki Kontakt z organizacją Opens in new window Strona internetowa Opens in new window Koszt całkowity Brak danych SWANSEA NHS TRUST Zjednoczone Królestwo Wkład UE € 19 458,00 Adres Morriston Hospital-Heol Maes Yr Eglwys SA6 6NL SWANSEA Zobacz na mapie Rodzaj działalności Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) Kontakt administracyjny Ciaran O'brien (Dr.) Linki Kontakt z organizacją Opens in new window Strona internetowa Opens in new window Koszt całkowity Brak danych THE ROYAL VETERINARY COLLEGE Zjednoczone Królestwo Wkład UE € 1 797,00 Adres ROYAL COLLEGE STREET NW1 OTU London Zobacz na mapie Region London Outer London — West and North West Barnet Rodzaj działalności Higher or Secondary Education Establishments Kontakt administracyjny Turhan Alasya (Mr.) Linki Kontakt z organizacją Opens in new window Strona internetowa Opens in new window Koszt całkowity Brak danych PORVAIR FILTRATION GROUP LIMITED Zjednoczone Królestwo Wkład UE € 31 592,00 Adres Fareham Industrial Park PO16 8XG Fareham Zobacz na mapie Rodzaj działalności Private for-profit entities (excluding Higher or Secondary Education Establishments) Kontakt administracyjny David Cowieson (Dr.) Linki Kontakt z organizacją Opens in new window Strona internetowa Opens in new window Koszt całkowity Brak danych