Objective
The introduction of transgenes that express fluorescent proteins (FPs) into cells has revolutionized the ability to visualize many cellular and sub-cellular processes that are otherwise invisible with traditional means of optical imaging. Fluorescent proteins have been widely used in microscopic imaging, however deep tissue imaging has not been possible, before the recent development of fluorescent proteins emitting beyond the 600 nm absorption threshold. In the present proposal the applicant will study and develop a novel optical tomographic method for preclinical research applications with the use of the recently evolved red-shifted fluorescent proteins. The development is going to be based on modifying the existing Fluorescence Molecular Tomography method both in its experimental and theoretical part as necessary. The result will be a tomographic method and system that will be used to reconstruct in 3D the location of the fluorescent proteins deep inside the tissue of small animals (mice) with submillimeter resolution. The proposed method/system will be tested against various of the parameters of its operation and will be used to demonstrate its use in in-vivo biomedical imaging applications. A method/system like the proposed has the potential to become a high capability non invasive monitoring and diagnostic tool in bio-medical research on small animals.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP7-PEOPLE-2007-2-1-IEF
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
85764 Neuherberg
Germany
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.