Objective
"This project aims to characterize, at the molecular level, the segments of the Brassica napus genome that contain the PrBn locus and a number of other additive or epistatic QTLs controlling homeologous recombination. We will first combine fine genetic mapping and comparative genomic approaches (using Arabidopsis thaliana) to test the core hypothesis that PrBn and most of the mapped QTLs belong to homeologous and / or paralogous regions originating from the amphidiploid nature of the B. napus genome and the large-scale ancestral genome triplication found in its diploid progenitors. We will then screen a B. napus BAC library with markers anchored in the corresponding regions, align the positive BACs into separate contigs spanning the targeted segments and thus generate ""draft"" physical maps of the PrBn region and its duplicates. We will use the rapidly developing genomic resources available for B. rapa and B. oleracea to identify the corresponding regions in the genome of these two diploid species, which are the closest living relatives of B. napus progenitors. This will thus allow a comparative analysis of the microstructure of the PrBn regions and its paralogues and lay the genomic foundation for the long term map-based cloning of PrBn. This project tackles two important aspects of genome evolution related to polyploidy, which is one of the most prominent evolutionary process in plants, including many important crops, and many other eukaryotes: it questions the evolutionary dynamics of duplicated genes/regions, which has a broad significance in biology, and addresses the question of genetic regulation of homeologous chromosome pairing and recombination in allopolyploid species, which is a prerequisite for proper chromosome segregation and reproductive stability in sexual polyploids."
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
- natural sciences biological sciences evolutionary biology
- agricultural sciences agriculture, forestry, and fisheries agriculture
- natural sciences biological sciences genetics chromosomes
- natural sciences biological sciences genetics genomes
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP7-PEOPLE-2007-2-1-IEF
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
75007 PARIS CEDEX 07
France
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.