Objective
Auxins are an important group of phytohormones, that regulate various aspects of embryonic and postembryonic development. Transduction of the auxin stimulus depends on selective protein degradation: it involves the activity of the TIR1 family receptors, that act in the SCF complex to target the family of Aux/IAA transcription factors for degradation. Although the core module of auxin signalling has been established, the mechanisms that modulate the signal flow are still only partially understood. A genetic screen performed in the host laboratory identified the advoluta (adv) mutant, which exhibits increased apical dominance and hyponastic leaves, suggesting an impaired auxin response. Moreover, preliminary analysis points to a complex genetic interaction between adv and the auxin response mutant axr1. Together this implies that ADV could be a novel component in auxin signalling. The objectives of this study are the characterisation of adv in the context of its putative involvement in the auxin signalling cascade, cloning of the adv mutation and the functional molecular analysis of the gene product. A wide set of modern techniques ranging from genetics and molecular biology to plant physiology and biochemistry will be employed in the project, including various specialised methods to asses auxin response. This study will likely allow us to define ADV as a novel element in auxin response, placing it in the signalling cascade and building a hypothesis regarding the gene’s molecular function. The proposed research training will enable the applicant to get acquainted with plant developmental biology and expand her knowledge in the field of phytohormone physiology and signalling. Apart from the research training, the applicant will acquire complementary skills (organisational and communication skills, project management). In conclusion, the proposed training will strongly advance and benefit the researcher’s career.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
- natural sciences biological sciences biochemistry biomolecules proteins
- natural sciences biological sciences developmental biology
- natural sciences biological sciences genetics mutation
- medical and health sciences basic medicine physiology
- natural sciences biological sciences molecular biology
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP7-PEOPLE-2007-2-1-IEF
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
YO10 5DD York North Yorkshire
United Kingdom
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.