Objective
Plants are constantly confronted by multiple types of nutritional, abiotic and biotic stress. Often associated with stress is a reduction in photosynthesis and/or respiration, which in turn results in energy deprivation and ultimately in growth arrest. Despite their distinct origin and mode of perception, different stresses trigger similar downstream responses that include largely overlapping patterns of gene expression. Our work has shown that this general stress transcriptome is partly regulated by the evolutionarily conserved energy sensor protein kinases, SNF1 (sucrose non-fermenting1) in yeast, AMPK (AMP-activated protein kinase) in mammals and SnRK1 (Snf1-related kinase1) in plants. Upon sensing the energy deficit associated with stress, SnRK1 triggers extensive transcriptional changes that contribute to restoring metabolic and energy homeostasis, promoting cell survival and allowing the elaboration of longer-term responses for adaptation, growth and development. Despite the importance of the uncovered energy signaling pathway, virtually nothing is known regarding its mode of operation. Using a combination of cell-based assays, functional genomics, bioinformatics, mutant screens and genetics, this proposal seeks to gain insight on the regulatory mechanisms that govern SnRK1 action and to further dissect this signaling pathway through the identification of novel components. Elucidation of these mechanisms will contribute to understanding how stress resistance is established and how plant growth and development are finely orchestrated by the environment.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences genetics
- natural sciences biological sciences biochemistry biomolecules proteins
- natural sciences biological sciences zoology mammalogy
- medical and health sciences basic medicine physiology homeostasis
- natural sciences biological sciences botany
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP7-PEOPLE-IRG-2008
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
1067-001 LISBOA
Portugal
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.