Objective
Many important biological systems have the ability of transferring mechanical energy within individual molecules across distances of 1-10 nm. The mechanisms behind such energy transfer are poorly understood. Increased knowledge about them may not only explain fundamental processes in biology, but may also enable novel approaches to energy-related problems in general and new applications in supramolecular nanotechnology in particular. We propose to use physico-chemical methods to study how chemical, electrical and photochemical energy is converted into mechanical energy in supramolecular systems as models for the biological systems. We will concentrate on the energy conversion in proteins: ATP synthase, ion channel KvAP and Rad51, which each exemplifies a different solution to intra-molecular energy transfer. To enhance our mechanistic understanding, we will use model systems and methods that have previously been developed in the laboratory. We intend to build on our extensive expertise in spectroscopic methodology and exploit and develop further site-selected linear dichroism by molecular replacement (SSLD-MR) for studying structure and dynamics of the systems and their components. The studies here described constitute a new direction of research and a unique approach to addressing fundamental questions on energy conversion in biological systems. The results may give insights into important events in biology and new methodologies that enable us for the first time to study structural details of membrane proteins in membrane environment.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences biochemistry biomolecules proteins
- engineering and technology nanotechnology
- engineering and technology environmental engineering energy and fuels energy conversion
You need to log in or register to use this function
We are sorry... an unexpected error occurred during execution.
You need to be authenticated. Your session might have expired.
Thank you for your feedback. You will soon receive an email to confirm the submission. If you have selected to be notified about the reporting status, you will also be contacted when the reporting status will change.
Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
ERC-2008-AdG
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Host institution
412 96 GOTEBORG
Sweden
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.