Objective
Modern molecular biology relies on high-throughput technologies to generate large quantities of data about components of living cells and on sophisticated mathematical and computational techniques for analyzing this data. We will develop new algorithms and probabilistic models in areas of comparative genomics, gene finding, and homology search. In particular, we propose a new class of evolutionary models for modeling changes in exon structure of protein coding genes. These models have applications in gene finding and ancestral sequence reconstruction. We will also develop more efficient methods for homology search in large databases containing families of related sequences. Finally, we will apply both existing and new methods to comparative analysis of mitochondrial genomes in Candida genus. Some of these genomes have linear chromosomes terminated with telomere-like structures similar to eukaryotic nuclear chromosomes, yet of independent evolutionary origin. By studying these sequences, we aim to address fundamental questions of evolution of linear genomes and telomeric regions, and evolution of binding specificity in DNA binding proteins. This interdisciplinary project will be carried out in cooperation with researchers from both computer science and biology at Comenius University in Bratislava.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
- natural sciences biological sciences genetics DNA
- natural sciences biological sciences biochemistry biomolecules proteins
- natural sciences biological sciences genetics chromosomes
- natural sciences biological sciences genetics genomes
- natural sciences biological sciences molecular biology molecular evolution
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP7-PEOPLE-IRG-2008
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
814 99 Bratislava
Slovakia
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.