Objective
There is a great need in today’s Europe for well trained researchers in the field of aging exercise biology. This is greatly boosted by the large increase in life expectancy and the pandemic incidence of obesity, diabetes 2 and dyslipidemias. Statins are the most effective drugs for the treatment of high cholesterol levels. However, statins are associated with several muscle problems, including rhabdomyolysis, muscle pain, weakness and cramps. These side-effects warrant attention because they limit the use of statins, decrease functional fitness and mobility as well as increase the risk of injury. This situation is particularly exacerbated in older individuals who are the major consumers of statins and who already suffer to some degree from muscle weakness. Therefore, the aim of the present study is to determine the effect of exercise –with or without prior statin administration– on skeletal muscle mass and function, physical performance, energy metabolism, blood and muscle lipid profile and oxidative stress, gait biomechanics, proprioception and quality of life. The proposed study will be the first to try to connect statins with muscle damage from molecular to organism level in an exercise context. Given the fact that taking statins combined with exercise is a very common practice, the results of this study may reveal evidence whether treatment with statins exerts beneficial, detrimental or no effects on human biology and health, particularly for the older exercising people. The fellow researcher has performed postgraduate studies in the field of exercise biology and is already director of a university-based exercise biology lab in his home country. The host institution is one of the few research institutes in Europe specializing on human biology and exercise. The scientist in charge is research lecturer in the host institute with strong experience in the field of exercise and muscle biology.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- medical and health sciences clinical medicine endocrinology diabetes
- natural sciences biological sciences biochemistry biomolecules lipids
- natural sciences biological sciences biophysics
- medical and health sciences health sciences nutrition obesity
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP7-PEOPLE-IEF-2008
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Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
38500 VOLOS
Greece
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.