Objective
The objective of this proposal is to improve analytical performance of Desorption Electrospray Ionization (DESI) coupled to a high resolution Fourier Transform Ion Cyclotron Resonance Mass Spectrometer (FT-ICR-MS) and gain more insight into the DESI mechanism and underlying processes. DESI is a novel ionization method, that combines features of electrospray ionization (ESI) with those of the family of desorption ionization (DI) methods. The DESI experiment allows molecules present on surfaces to be analyzed by mass spectrometry without requiring the sample to be introduced into the vacuum system of the mass spectrometer. DESI differentiates itself from other DI methods in mass spectrometry because the sample can be analyzed outside the mass spectrometer in an open laboratory environment. There is virtually no sample handling in DESI and no ionization matrix needs to be added to the sample; the sample is sprayed with charged microdroplets of solvent (e.g. water, methanol etc.), delivered by a simply modified electrospray emitter (electrosonic electrospray or ESSI). DESI proved itself to be a useful tool in a very wide range of disciplines from traditional chemical and pharmaceutical process and quality control to more exotic applications including dactyloscopy and tissue imaging. Most of the interest in DESI inside mass spectrometry community is chiefly in the analytical applications area. There have only been handful reports focused on DESI theory and mechanism. Thus, the fundamental processes in DESI are not fully understood and despite many advantages DESI also suffers limitations, especially relatively poor Limit of Detection (LOD) compared to competing mass spectrometry techniques. The analytical figures of merit will play more significant role in the near future because two dimensional DESI imaging is currently being introduced. That is why this proposal is focused on investigation of fundamental surface processes in DESI and its overall improvement.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
- natural sciences physical sciences theoretical physics particle physics particle accelerator
- natural sciences chemical sciences organic chemistry alcohols
- natural sciences chemical sciences analytical chemistry mass spectrometry
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP7-PEOPLE-IRG-2008
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Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
142 00 Praha 4
Czechia
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.