Objective
Cerebrovascular disease (CVD) is a very significant health problem, especially in view of the increasing aging population. It is highly prevalent in diabetic populations and is also a major cause of dementia, individually or as an additive factor to other pathologies, such as Alzheimer’s. Therefore measuring disease burden, progression, and response to treatments is very important for patient management. MRI is currently the most widely used way to characterize in vivo the type and extent of brain lesions in CVD and has been used in several large neuroimaging studies. However, characterization of CVD has largely relied on qualitative, subjective, and not easily reproducible methods of human expert-based interpretation. Computer-based methods for measuring CVD offer great potential, since they are quantitative; reproducible, and particularly suitable for longitudinal studies monitoring disease progression and response to candidate treatments. Most methods have focused on the segmentation of Multiple Sclerosis lesions, whereas less attention has been given to brain lesion segmentation in elderly individuals and Alzheimer’s disease or diabetic patients.
The project DeBrA (Detection of Brain Abnormality) includes the development and implementation of medical imaging techniques for measuring CVD and its change over time, from multi-parametric MR images by employing advanced 4-dimensional (space X time) segmentation methods based on pattern classification and statistical modeling. The goal is to determine whether the new methodology will provide more stable measurements of longitudinal change in CVD, compared to relatively more conventional methods and therefore increase the sensitivity of detecting subtle effects. Moreover, while the tools will be initially developed for measuring CVD, they will be made suitable to hold widespread potential for applications in other neuroimaging studies involving abnormality detection.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- medical and health sciences basic medicine neurology dementia alzheimer
- medical and health sciences basic medicine neurology multiple sclerosis
- medical and health sciences basic medicine pathology
- engineering and technology medical engineering diagnostic imaging
- medical and health sciences clinical medicine angiology vascular diseases cerebrovascular diseases
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP7-PEOPLE-IRG-2008
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
265 04 RIO PATRAS
Greece
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.