Objective
Diagnostics impact our lives in many ways, including disease diagnosis, treatment monitoring and long term environmental biomonitoring. The value of biomarker research in the field of diagnostics and predictive medicine has long been acknowledged. There is an increasing realisation that proteins and peptides mediate a rich information stream reporting on the health of an individual and the emergent techniques of proteomics have made possible the identification, characterisation and quantification of vanishingly low quantities of proteins in complex biological fluids. The analysis of the typical protein pattern from a pathological state by proteomics technology offers the opportunity to discover potentially new biomarkers for premature diagnosis and prognosis. Early developments in proteome analysis were based on protein separation through electrophoresis but it was the development of ‘soft’ ionisation modes and extended mass ranges in mass spectrometry which transformed the subject. Although the hold grail of proteomics (the complete characterisation and quantification of every protein in a cell) has not yet been met, the field has experienced some notable successes, and there has been a remarkable expansion of interest in the ten years passed since the term was first coined, (pubmed: 11 references containing the term ‘proteomics’ in 1996, over 12,000 papers in 2006). One of the areas in which proteomics can contribute a lot is that of biomarkers discovery and quantification. In this project we propose the combination of several novel proteomics approaches namely, positional proteomics, protein equalizer technology and absolute multiplexed quantification (QconCAT), to improve the efficiency of protein and peptide based biomarkers for animal disease diagnosis and monitoring. We will specifically apply these technologies to current challenges in animal health, an area largely left out if compared with human health.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
- natural sciences biological sciences biochemistry biomolecules proteins proteomics
- natural sciences chemical sciences electrochemistry electrophoresis
- natural sciences chemical sciences analytical chemistry mass spectrometry
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP7-PEOPLE-IEF-2008
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
L69 7ZX LIVERPOOL
United Kingdom
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.