Objectif Schizophrenia and bipolar affective disorder are a major burden to affected individuals and their families and to society at large. These two severe mental illnesses affect at least 2% of the population worldwide, and whilst 50% of sufferers do not receive adequate treatment, they cost hundreds of billions in healthcare provision, treatments and lost earnings. The current diagnosis of schizophrenia (and bipolar disorder etc.) is rather subjective, not only because of the complex spectrum of symptoms and their similarity to other mental disorders, but also due to the lack of empirical disease markers. This result in long delays (up to 1-3 years) before appropriate therapeutics is prescribed to first episode schizophrenics. Early treatment is associated with greatly improved patient outcomes. There is therefore a major unmet clinical need for empirical diagnostic tests for high throughput screening of biological fluids that would enable early and accurate diagnosis of schizophrenia and related disorders. The identification of specific biomarkers for mental disorders would revolutionise the clinical management of affected individuals. Biomarkers will help in the identification of disease sub-types, aid in predicting and monitoring treatment response and compliance, and identify novel drug targets. If such biomarkers can be found in readily accessible body fluids they open up the possibility of developing new early or pre-symptomatic diagnostics and/or treatments to improve outcomes or even prevent disease. The objective of our project is to identify biomarkers of disease and develop a diagnostic assay panel/tool for the high throughput screening of biological samples for clinical research. Moreover this platform will be utilised by SMEs for drug design and development for mental disorders research into new animal models for mental dirders and identifying biomarkers for other mental disorders Champ scientifique medical and health sciencesbasic medicinemedicinal chemistrymedical and health sciencesclinical medicinepsychiatryschizophrenia Mots‑clés Clinical research bipolar disorder early diagnosis high throughput technologies mental disorders proteomics schizophrenia Programme(s) FP7-HEALTH - Specific Programme "Cooperation": Health Thème(s) HEALTH-2007-1.1-4 - SME-driven collaborative research projects for developing tools and technologies for high-throughput research Appel à propositions FP7-HEALTH-2007-B Voir d’autres projets de cet appel Régime de financement CP-TP - Collaborative Project targeted to a special group (such as SMEs) Coordinateur Psynova Neurotech Ltd Contribution de l’UE € 373 354,00 Adresse St, Johns Innovation Centre, Cowley Road CB4 0WS Cambridge Royaume-Uni Voir sur la carte Type d’activité Private for-profit entities (excluding Higher or Secondary Education Establishments) Contact administratif Barbara Baron (Ms.) Liens Contacter l’organisation Opens in new window Site web Opens in new window Coût total Aucune donnée Participants (8) Trier par ordre alphabétique Trier par contribution de l’UE Tout développer Tout réduire THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE Royaume-Uni Contribution de l’UE € 463 290,00 Adresse TRINITY LANE THE OLD SCHOOLS CB2 1TN Cambridge Voir sur la carte Région East of England East Anglia Cambridgeshire CC Type d’activité Higher or Secondary Education Establishments Contact administratif Dawn Barker (Ms.) Liens Contacter l’organisation Opens in new window Site web Opens in new window Coût total Aucune donnée ZENTRALINSTITUT FUER SEELISCHE GESUNDHEIT Allemagne Contribution de l’UE € 360 387,00 Adresse Square J 5 68159 Mannheim Voir sur la carte Région Baden-Württemberg Karlsruhe Mannheim, Stadtkreis Type d’activité Higher or Secondary Education Establishments Contact administratif Simone Fuchs (Ms.) Liens Contacter l’organisation Opens in new window Site web Opens in new window Coût total Aucune donnée Westfälische Wilhelms-Universität Münster Allemagne Contribution de l’UE € 360 387,00 Adresse SCHLOSSPLATZ 2 48149 MUENSTER Voir sur la carte Région Nordrhein-Westfalen Münster Münster, Kreisfreie Stadt Type d’activité Higher or Secondary Education Establishments Contact administratif Karl-Heinz Runde (Mr.) Liens Contacter l’organisation Opens in new window Site web Opens in new window Coût total Aucune donnée EDI Experimentelle Diagnostische Immunologie GmbH Allemagne Contribution de l’UE € 301 300,00 Adresse Aspenhaustrasse 72770 Reutlingen Voir sur la carte Type d’activité Private for-profit entities (excluding Higher or Secondary Education Establishments) Contact administratif Thomas Joos (Dr.) Liens Contacter l’organisation Opens in new window Site web Opens in new window Coût total Aucune donnée PERA INNOVATION LIMITED Royaume-Uni Contribution de l’UE € 175 220,00 Adresse Innovation Park, Nottingham Road LE13 OPB MELTON MOWBRAY, LEICESTERSHIRE Voir sur la carte Type d’activité Research Organisations Contact administratif David Cartlidge (Mr.) Liens Contacter l’organisation Opens in new window Site web Opens in new window Coût total Aucune donnée NATIONAL INSTITUTE FOR BIOPROCESSING RESEARCH AND TRAINING LIMITED Irlande Contribution de l’UE € 206 050,00 Adresse FOSTERS AVENUE MOUNT MERRION 4 Blackrock Dublin Voir sur la carte Région Ireland Eastern and Midland Dublin Type d’activité Other Contact administratif Pauline Rudd (Prof.) Liens Contacter l’organisation Opens in new window Site web Opens in new window Coût total Aucune donnée STORKBIO Estonie Contribution de l’UE € 147 056,00 Adresse LAKI 25 12915 TALLINN Voir sur la carte Type d’activité Private for-profit entities (excluding Higher or Secondary Education Establishments) Contact administratif Kristi Kurg (Ms.) Liens Contacter l’organisation Opens in new window Site web Opens in new window Coût total Aucune donnée MYRIAD RBM INC CORPORATION États-Unis Contribution de l’UE € 370 644,00 Adresse Duval Road 3300 TX 78759 Austin Voir sur la carte Type d’activité Private for-profit entities (excluding Higher or Secondary Education Establishments) Contact administratif Sam Labrie (Mr.) Liens Contacter l’organisation Opens in new window Site web Opens in new window Coût total Aucune donnée