Obiettivo Schizophrenia and bipolar affective disorder are a major burden to affected individuals and their families and to society at large. These two severe mental illnesses affect at least 2% of the population worldwide, and whilst 50% of sufferers do not receive adequate treatment, they cost hundreds of billions in healthcare provision, treatments and lost earnings. The current diagnosis of schizophrenia (and bipolar disorder etc.) is rather subjective, not only because of the complex spectrum of symptoms and their similarity to other mental disorders, but also due to the lack of empirical disease markers. This result in long delays (up to 1-3 years) before appropriate therapeutics is prescribed to first episode schizophrenics. Early treatment is associated with greatly improved patient outcomes. There is therefore a major unmet clinical need for empirical diagnostic tests for high throughput screening of biological fluids that would enable early and accurate diagnosis of schizophrenia and related disorders. The identification of specific biomarkers for mental disorders would revolutionise the clinical management of affected individuals. Biomarkers will help in the identification of disease sub-types, aid in predicting and monitoring treatment response and compliance, and identify novel drug targets. If such biomarkers can be found in readily accessible body fluids they open up the possibility of developing new early or pre-symptomatic diagnostics and/or treatments to improve outcomes or even prevent disease. The objective of our project is to identify biomarkers of disease and develop a diagnostic assay panel/tool for the high throughput screening of biological samples for clinical research. Moreover this platform will be utilised by SMEs for drug design and development for mental disorders research into new animal models for mental dirders and identifying biomarkers for other mental disorders Campo scientifico medical and health sciencesbasic medicinemedicinal chemistrymedical and health sciencesclinical medicinepsychiatryschizophrenia Parole chiave Clinical research bipolar disorder early diagnosis high throughput technologies mental disorders proteomics schizophrenia Programma(i) FP7-HEALTH - Specific Programme "Cooperation": Health Argomento(i) HEALTH-2007-1.1-4 - SME-driven collaborative research projects for developing tools and technologies for high-throughput research Invito a presentare proposte FP7-HEALTH-2007-B Vedi altri progetti per questo bando Meccanismo di finanziamento CP-TP - Collaborative Project targeted to a special group (such as SMEs) Coordinatore Psynova Neurotech Ltd Contributo UE € 373 354,00 Indirizzo St, Johns Innovation Centre, Cowley Road CB4 0WS Cambridge Regno Unito Mostra sulla mappa Tipo di attività Private for-profit entities (excluding Higher or Secondary Education Establishments) Contatto amministrativo Barbara Baron (Ms.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato Partecipanti (8) Classifica in ordine alfabetico Classifica per Contributo UE Espandi tutto Riduci tutto THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE Regno Unito Contributo UE € 463 290,00 Indirizzo TRINITY LANE THE OLD SCHOOLS CB2 1TN Cambridge Mostra sulla mappa Regione East of England East Anglia Cambridgeshire CC Tipo di attività Higher or Secondary Education Establishments Contatto amministrativo Dawn Barker (Ms.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato ZENTRALINSTITUT FUER SEELISCHE GESUNDHEIT Germania Contributo UE € 360 387,00 Indirizzo Square J 5 68159 Mannheim Mostra sulla mappa Regione Baden-Württemberg Karlsruhe Mannheim, Stadtkreis Tipo di attività Higher or Secondary Education Establishments Contatto amministrativo Simone Fuchs (Ms.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato Westfälische Wilhelms-Universität Münster Germania Contributo UE € 360 387,00 Indirizzo SCHLOSSPLATZ 2 48149 MUENSTER Mostra sulla mappa Regione Nordrhein-Westfalen Münster Münster, Kreisfreie Stadt Tipo di attività Higher or Secondary Education Establishments Contatto amministrativo Karl-Heinz Runde (Mr.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato EDI Experimentelle Diagnostische Immunologie GmbH Germania Contributo UE € 301 300,00 Indirizzo Aspenhaustrasse 72770 Reutlingen Mostra sulla mappa Tipo di attività Private for-profit entities (excluding Higher or Secondary Education Establishments) Contatto amministrativo Thomas Joos (Dr.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato PERA INNOVATION LIMITED Regno Unito Contributo UE € 175 220,00 Indirizzo Innovation Park, Nottingham Road LE13 OPB MELTON MOWBRAY, LEICESTERSHIRE Mostra sulla mappa Tipo di attività Research Organisations Contatto amministrativo David Cartlidge (Mr.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato NATIONAL INSTITUTE FOR BIOPROCESSING RESEARCH AND TRAINING LIMITED Irlanda Contributo UE € 206 050,00 Indirizzo FOSTERS AVENUE MOUNT MERRION 4 Blackrock Dublin Mostra sulla mappa Regione Ireland Eastern and Midland Dublin Tipo di attività Other Contatto amministrativo Pauline Rudd (Prof.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato STORKBIO Estonia Contributo UE € 147 056,00 Indirizzo LAKI 25 12915 TALLINN Mostra sulla mappa Tipo di attività Private for-profit entities (excluding Higher or Secondary Education Establishments) Contatto amministrativo Kristi Kurg (Ms.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato MYRIAD RBM INC CORPORATION Stati Uniti Contributo UE € 370 644,00 Indirizzo Duval Road 3300 TX 78759 Austin Mostra sulla mappa Tipo di attività Private for-profit entities (excluding Higher or Secondary Education Establishments) Contatto amministrativo Sam Labrie (Mr.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato