Objective The first objective is to identify the relative importance of the different sources of calcium during critical phases of development, growth and reproduction during a normal production cycle on a fish farm. The second objective is to determine experimentally whole animal calcium homeostasis during larval development, vitellogenesis and normal growth and the role of PTHrP in maintaining homeostasis. These will be related to observations of calcium requirements and balance made on the fish farm. The third objective will be to determine the molecular mechanisms, which underpin bone formation in fish and the way in which PTHrP regulates this process.The PTHrP gene promoter(s) will be identified and used to characterise factors, which may influence its expression in vivo. Genes differentially expressed during endochondral bone formation, and thus strong candidate genes for this process will be isolated and their regulation by PTHrP determined. Fields of science natural scienceschemical sciencesinorganic chemistryalkaline earth metalsmedical and health sciencesbasic medicinephysiologyhomeostasis Programme(s) FP5-LIFE QUALITY - Specific Programme for research, technological development and demonstration on "Quality of life and management of living resources", 1998-2002 Topic(s) Data not available Call for proposal 2 See other projects for this call Funding Scheme Data not available Coordinator UNIVERSIDADE DO ALGARVE EU contribution No data Address Campus de Gambelas FARO Portugal See on map Total cost No data Participants (7) Sort alphabetically Sort by EU Contribution Expand all Collapse all DOUBLE DELTA KERESKEDELMI TERMELO ES KUTATASFEJLESZTESI BETETI TARSASAG Hungary EU contribution No data Address Hullam 12 BERETTYOUJFALU See on map Total cost No data KATHOLIEKE UNIVERSITEIT NIJMEGEN Netherlands EU contribution No data Address Toernooiveld 1 NIJMEGEN See on map Total cost No data MEDICAL RESEARCH COUNCIL United Kingdom EU contribution No data Address Wellcome Genome Campus Hinxton CAMBRIDGE See on map Total cost No data NATURAL ENVIRONMENT RESEARCH COUNCIL United Kingdom EU contribution No data Address High Cross Madingley Road CAMBRIDGE See on map Total cost No data POLISH ACADEMY OF SCIENCES INSTITUTE OF OCEANOLOGY Poland EU contribution No data Address Powstancow Warszawy, 55 SOPOT See on map Total cost No data UNIVERSITY OF MANCHESTER United Kingdom EU contribution No data Address Oxford Road MANCHESTER See on map Links Website Opens in new window Total cost No data VIVEIRO VILANOVA S.A. Portugal EU contribution No data Address Foros do Galeado VILA NOVA DE MILFONTES See on map Total cost No data