Objective
In the METAPRO project we aim to optimise the production of several useful isoprenoid derived secondary metabolites to demonstrate the tools and strategies developed for the generic production of useful secondary metabolites in plants. Astaxanthin (ketocarotenoids) and the apocarotenoid crocin have been selected to demonstrate the application of the technologies adopted and developed. These compounds are of high-value and used in the industrial and health sectors. Both are classical secondary plant metabolites being formed in slow growing species that are not readily amenable to agricultural production. They are non-essential to the plant, synthesised at a defined developmental stage, in specialised tissues, cells and/or cellular compartments. In order to generate cheap renewable bio-resources of these compounds with improved economic and environmental potential, natural variation will be exploited and genetic engineering approaches implemented. Astaxanthin and crocin will be engineered into Solanaceae host platforms. Tomato fruit and potato tuber are ideal cell factories for this class of molecules, as at defined developmental stages their tissues and specialised cellular compartments are pre-disposed to high level isoprenoid formation. To optimise production in these hosts the METAPRO project aims to use modern and emerging technologies to (i) elucidate regulatory mechanisms involved in synthesis, (ii) optimise storage by increasing, altering and transport from, the cellular compartment responsible for synthesis and accumulation, (iii) improve stability of the products in the cell and during bioprocessing and (iv) implement improved transformation, transcription and translation tools for more efficient engineering and improved yields and quality. To achieve these objectives and deliver scientific excellence with impact a multidisciplinary pan-European team with complementary expertise, industrial (SME) participation and global interaction has been constructed.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
- agricultural sciences agriculture, forestry, and fisheries agriculture horticulture fruit growing
- medical and health sciences medical biotechnology genetic engineering
- agricultural sciences agriculture, forestry, and fisheries agriculture horticulture vegetable growing root crops
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP7-KBBE-2009-3
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
TW20 0EX Egham
United Kingdom
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.