Objective
In the past decade, development of biomimetic ligands have enabled rapid advances as alternative candidates to antibodies in many biotechnology fields. The Research will focus on the development of a new generation of biomimetic sensors for food safety and quality monitoring. The approach of the project will be oriented to test the performances of enzymes or antibodies versus new computationally-designed biomimetic ligands which work by mimicking the biological binding site. In particular it will be tested the performances of new computationally-designed biomimetic ligands which work as mimicking the biological binding site, overcoming the disadvantages of biological materials (unstable, expensive to produce) and matching the continuous trend to reduce the use of animals for the production of biological reagents. Choosing a ligand to achieve some desired structure is still largely a subject of trial and error. The key point of this research will be taking advantage of molecular modelling to obtain candidates with the aim of reducing to orders of magnitude the efforts to obtain specific receptors. These new ligands will be coupled with different transducers used in sensors technology known to give fast, reproducible and sensible analytical responses often in real time. This approach is promising to produce inexpensive biotechnological devices to be used in food safety and quality monitoring by combining the selectivity of biomimetic ligands with abiotic properties such as greater stability in harsh environments, with the powerful properties of biosensing techniques. All important analytical parameters i.e. reproducibility, sensitivity, selectivity, stability, etc, will be studied. first using standards and, after optimization of the protocol, on real samples. As model, typical food target will be used such as xenobiotics.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- engineering and technology other engineering and technologies food technology food safety
- engineering and technology electrical engineering, electronic engineering, information engineering electronic engineering sensors
- natural sciences biological sciences biochemistry biomolecules proteins enzymes
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP7-PEOPLE-IRSES-2008
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
MC-IRSES - International research staff exchange scheme (IRSES)
Coordinator
64100 Teramo
Italy
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.