Objective
The study of experimental pattern formation mechanisms and its relevance to biology has been restricted to nonlinear chemical systems that produce spatial Turing patterns (CDIMA reaction), spiral waves (BZ reaction), propagating fronts and pulses (GO reaction). The important differences between these artificial systems and the natural spatial differentiation occurring in living cells do not allow for direct application of nonlinear dynamics tools to analyze biological patterns. The complexity of living organisms is also complicating the understanding of the underlying mechanisms for the arising of living patterns, therefore a much simpler symmetry breaking mechanism in living cells will allow a closer connection between developmental biologists and nonlinear physicists. The implementation of a spontaneous symmetry breaking mechanism in tissue culture mammalian cells using engineered cell-to-cell communication will constitute a highly improved model system for morphogenesis, early embryo development and skin patterning. This mechanism will be implemented using a highly interdisciplinary approach combining experimental /theoretical experience in chemical symmetry breaking systems and nonlinear physics tools together with a background in synthetic biology and signaling pathways. The candidate background in pattern formation, biophysics and cell biology combined with the expertise of the host laboratory (Elisa Martí at the Parc Cientific of Barcelona University) in symmetry breaking during early development constitute the perfect complement to carry out this type of research. An in-vitro pattern formation system will change the way biologists and physicists interact to understand the complexity of self-organization in living organisms.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
- natural sciences biological sciences synthetic biology
- natural sciences biological sciences cell biology
- natural sciences biological sciences biophysics
- medical and health sciences clinical medicine embryology
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP7-PEOPLE-2009-RG
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
28006 MADRID
Spain
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.