Objetivo Since the histopathological diagnosis of tumours is based on microscopy, it would be highly desirable to possess a microscopical technique allowing morphological investigation with a wide zoom range, high resolution and the implementation of multiplex staining. Thus, the goal of the REMEDI project is to explore the possibilites of novel light microscopy techniques, which overcome the diffraction limit of visible light and extend the range of observation to the molecular level of proteins in tumour cells and analyze their interaction and spatial distribution. This proposal aims at the use of single-molecule-microscopy of cancer tissue samples with ultra-high sensitivity, simplified handling and increased speed of analysis. This shall be accomplished by the development of a novel resolution-enhanced microscopy platform with an integrated novel CMOS camera and an adequate image acquistion and analysis software. The REMEDI platform will be validated with two relevant applications: diagnostic/experimental pathology of breast cancer and alterations of plasma membrane components of lymphoma cells. Ámbito científico natural sciencescomputer and information sciencessoftwareengineering and technologyelectrical engineering, electronic engineering, information engineeringelectronic engineeringsensorsoptical sensorsnatural sciencesbiological sciencesbiochemistrybiomoleculesproteinsnatural sciencesphysical sciencesopticsmicroscopymedical and health sciencesclinical medicineoncologybreast cancer Programa(s) FP7-HEALTH - Specific Programme "Cooperation": Health Tema(s) HEALTH-2009-1.2-1 - Development of tools for sensitive and specific in vitro detection of proteins and their interactions for diagnostic, prognostic and monitoring purposes Convocatoria de propuestas FP7-HEALTH-2009-single-stage Consulte otros proyectos de esta convocatoria Régimen de financiación CP-FP - Small or medium-scale focused research project Coordinador TILL I.D. GMBH Aportación de la UE € 710 000,00 Dirección Bahnhofstrasse 89 82166 Grafelfing Alemania Ver en el mapa Tipo de actividad Private for-profit entities (excluding Higher or Secondary Education Establishments) Contacto administrativo Stefanie Graf (Dr.) Enlaces Contactar con la organización Opens in new window Coste total Sin datos Participantes (4) Ordenar alfabéticamente Ordenar por aportación de la UE Ampliar todo Contraer todo ANDOR TECHNOLOGY LIMITED Reino Unido Aportación de la UE € 160 400,00 Dirección Millennium way 7 springvale business park BT12 7AL Belfast Ver en el mapa Región Northern Ireland Northern Ireland Belfast Tipo de actividad Private for-profit entities (excluding Higher or Secondary Education Establishments) Contacto administrativo Lynne Cross (Ms.) Enlaces Contactar con la organización Opens in new window Coste total Sin datos GEMEINSCHAFTSPRAXIS PROF DR MED AXEL NIENDORF DR MED SYLVIA BROCKMOLLER DR MED ANNEGRET DEBUS GBR Alemania Aportación de la UE € 207 000,00 Dirección Lornsenstrasse 4 22767 Hamburg Ver en el mapa Tipo de actividad Private for-profit entities (excluding Higher or Secondary Education Establishments) Contacto administrativo Axel Niendorf (Prof.) Enlaces Contactar con la organización Opens in new window Sitio web Opens in new window Coste total Sin datos STICHTING RADBOUD UNIVERSITEIT Países Bajos Aportación de la UE € 199 600,00 Dirección Houtlaan 4 6525 XZ Nijmegen Ver en el mapa Región Oost-Nederland Gelderland Arnhem/Nijmegen Tipo de actividad Higher or Secondary Education Establishments Contacto administrativo Sandy Devue-Budde (Ms.) Enlaces Contactar con la organización Opens in new window Sitio web Opens in new window Coste total Sin datos TILL PHOTONICS GMBH Alemania Aportación de la UE € 303 100,00 Dirección Lochhamer schlag 21 82166 Grafelfing Ver en el mapa Tipo de actividad Private for-profit entities (excluding Higher or Secondary Education Establishments) Contacto administrativo Jan Seele (Dr.) Enlaces Contactar con la organización Opens in new window Sitio web Opens in new window Coste total Sin datos