Objectif Since the histopathological diagnosis of tumours is based on microscopy, it would be highly desirable to possess a microscopical technique allowing morphological investigation with a wide zoom range, high resolution and the implementation of multiplex staining. Thus, the goal of the REMEDI project is to explore the possibilites of novel light microscopy techniques, which overcome the diffraction limit of visible light and extend the range of observation to the molecular level of proteins in tumour cells and analyze their interaction and spatial distribution. This proposal aims at the use of single-molecule-microscopy of cancer tissue samples with ultra-high sensitivity, simplified handling and increased speed of analysis. This shall be accomplished by the development of a novel resolution-enhanced microscopy platform with an integrated novel CMOS camera and an adequate image acquistion and analysis software. The REMEDI platform will be validated with two relevant applications: diagnostic/experimental pathology of breast cancer and alterations of plasma membrane components of lymphoma cells. Champ scientifique natural sciencescomputer and information sciencessoftwareengineering and technologyelectrical engineering, electronic engineering, information engineeringelectronic engineeringsensorsoptical sensorsnatural sciencesbiological sciencesbiochemistrybiomoleculesproteinsnatural sciencesphysical sciencesopticsmicroscopymedical and health sciencesclinical medicineoncologybreast cancer Programme(s) FP7-HEALTH - Specific Programme "Cooperation": Health Thème(s) HEALTH-2009-1.2-1 - Development of tools for sensitive and specific in vitro detection of proteins and their interactions for diagnostic, prognostic and monitoring purposes Appel à propositions FP7-HEALTH-2009-single-stage Voir d’autres projets de cet appel Régime de financement CP-FP - Small or medium-scale focused research project Coordinateur TILL I.D. GMBH Contribution de l’UE € 710 000,00 Adresse Bahnhofstrasse 89 82166 Grafelfing Allemagne Voir sur la carte Type d’activité Private for-profit entities (excluding Higher or Secondary Education Establishments) Contact administratif Stefanie Graf (Dr.) Liens Contacter l’organisation Opens in new window Coût total Aucune donnée Participants (4) Trier par ordre alphabétique Trier par contribution de l’UE Tout développer Tout réduire ANDOR TECHNOLOGY LIMITED Royaume-Uni Contribution de l’UE € 160 400,00 Adresse Millennium way 7 springvale business park BT12 7AL Belfast Voir sur la carte Région Northern Ireland Northern Ireland Belfast Type d’activité Private for-profit entities (excluding Higher or Secondary Education Establishments) Contact administratif Lynne Cross (Ms.) Liens Contacter l’organisation Opens in new window Coût total Aucune donnée GEMEINSCHAFTSPRAXIS PROF DR MED AXEL NIENDORF DR MED SYLVIA BROCKMOLLER DR MED ANNEGRET DEBUS GBR Allemagne Contribution de l’UE € 207 000,00 Adresse Lornsenstrasse 4 22767 Hamburg Voir sur la carte Type d’activité Private for-profit entities (excluding Higher or Secondary Education Establishments) Contact administratif Axel Niendorf (Prof.) Liens Contacter l’organisation Opens in new window Site web Opens in new window Coût total Aucune donnée STICHTING RADBOUD UNIVERSITEIT Pays-Bas Contribution de l’UE € 199 600,00 Adresse Houtlaan 4 6525 XZ Nijmegen Voir sur la carte Région Oost-Nederland Gelderland Arnhem/Nijmegen Type d’activité Higher or Secondary Education Establishments Contact administratif Sandy Devue-Budde (Ms.) Liens Contacter l’organisation Opens in new window Site web Opens in new window Coût total Aucune donnée TILL PHOTONICS GMBH Allemagne Contribution de l’UE € 303 100,00 Adresse Lochhamer schlag 21 82166 Grafelfing Voir sur la carte Type d’activité Private for-profit entities (excluding Higher or Secondary Education Establishments) Contact administratif Jan Seele (Dr.) Liens Contacter l’organisation Opens in new window Site web Opens in new window Coût total Aucune donnée