Obiettivo Since the histopathological diagnosis of tumours is based on microscopy, it would be highly desirable to possess a microscopical technique allowing morphological investigation with a wide zoom range, high resolution and the implementation of multiplex staining. Thus, the goal of the REMEDI project is to explore the possibilites of novel light microscopy techniques, which overcome the diffraction limit of visible light and extend the range of observation to the molecular level of proteins in tumour cells and analyze their interaction and spatial distribution. This proposal aims at the use of single-molecule-microscopy of cancer tissue samples with ultra-high sensitivity, simplified handling and increased speed of analysis. This shall be accomplished by the development of a novel resolution-enhanced microscopy platform with an integrated novel CMOS camera and an adequate image acquistion and analysis software. The REMEDI platform will be validated with two relevant applications: diagnostic/experimental pathology of breast cancer and alterations of plasma membrane components of lymphoma cells. Campo scientifico natural sciencescomputer and information sciencessoftwareengineering and technologyelectrical engineering, electronic engineering, information engineeringelectronic engineeringsensorsoptical sensorsnatural sciencesbiological sciencesbiochemistrybiomoleculesproteinsnatural sciencesphysical sciencesopticsmicroscopymedical and health sciencesclinical medicineoncologybreast cancer Programma(i) FP7-HEALTH - Specific Programme "Cooperation": Health Argomento(i) HEALTH-2009-1.2-1 - Development of tools for sensitive and specific in vitro detection of proteins and their interactions for diagnostic, prognostic and monitoring purposes Invito a presentare proposte FP7-HEALTH-2009-single-stage Vedi altri progetti per questo bando Meccanismo di finanziamento CP-FP - Small or medium-scale focused research project Coordinatore TILL I.D. GMBH Contributo UE € 710 000,00 Indirizzo Bahnhofstrasse 89 82166 Grafelfing Germania Mostra sulla mappa Tipo di attività Private for-profit entities (excluding Higher or Secondary Education Establishments) Contatto amministrativo Stefanie Graf (Dr.) Collegamenti Contatta l’organizzazione Opens in new window Costo totale Nessun dato Partecipanti (4) Classifica in ordine alfabetico Classifica per Contributo UE Espandi tutto Riduci tutto ANDOR TECHNOLOGY LIMITED Regno Unito Contributo UE € 160 400,00 Indirizzo Millennium way 7 springvale business park BT12 7AL Belfast Mostra sulla mappa Regione Northern Ireland Northern Ireland Belfast Tipo di attività Private for-profit entities (excluding Higher or Secondary Education Establishments) Contatto amministrativo Lynne Cross (Ms.) Collegamenti Contatta l’organizzazione Opens in new window Costo totale Nessun dato GEMEINSCHAFTSPRAXIS PROF DR MED AXEL NIENDORF DR MED SYLVIA BROCKMOLLER DR MED ANNEGRET DEBUS GBR Germania Contributo UE € 207 000,00 Indirizzo Lornsenstrasse 4 22767 Hamburg Mostra sulla mappa Tipo di attività Private for-profit entities (excluding Higher or Secondary Education Establishments) Contatto amministrativo Axel Niendorf (Prof.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato STICHTING RADBOUD UNIVERSITEIT Paesi Bassi Contributo UE € 199 600,00 Indirizzo Houtlaan 4 6525 XZ Nijmegen Mostra sulla mappa Regione Oost-Nederland Gelderland Arnhem/Nijmegen Tipo di attività Higher or Secondary Education Establishments Contatto amministrativo Sandy Devue-Budde (Ms.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato TILL PHOTONICS GMBH Germania Contributo UE € 303 100,00 Indirizzo Lochhamer schlag 21 82166 Grafelfing Mostra sulla mappa Tipo di attività Private for-profit entities (excluding Higher or Secondary Education Establishments) Contatto amministrativo Jan Seele (Dr.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato