Community Research and Development Information Service - CORDIS

FP7 PONTE

PONTE

Project reference: 247945
Funded under

Efficient Patient Recruitment for Innovative Clinical Trials of Existing Drugs to other Indications

From 2010-03-01 to 2013-02-28, closed project

Project details

Total cost:

EUR 3 276 699

EU contribution:

EUR 2 495 024

Coordinated in:

Belgium

Call for proposal:

FP7-ICT-2009-4See other projects for this call

Funding scheme:

CP - Collaborative project (generic)

PONTE is a European project standing for Efficient Patient Recruitment for Innovative Clinical Trials of Existing Drugs to other Indications.

PONTE provides a platform following a Service Oriented Architecture (SOA) approach that offers intelligent automatic identification of individuals eligible to participate in clinical trials (concerning their safety and clinical trial efficacy). The trials will be designed and planned through a flexible authoring tool, enabling semantic interoperability of clinical care information systems with clinical research information systems and drug and disease knowledge databases, as well as the appliance of advanced data mining techniques and enhanced learning algorithms.

Objective

Clinical trials are increasingly considered to be not only a means for evaluating the effectiveness of new medicine and pharmaceutical formulas but also for experimenting on existing drugs and their appliance to new diseases and disorders. Pharmaceutical companies tend to prefer launching modified versions of existing drugs, which generate generous profits while carrying little risk of rejection. Translation into clinical therapy has to overcome substantial barriers at the preclinical and clinical levels. Thus, bridging basic science to clinical practice comprises a new scientific challenge which can result in successful clinical applications with low financial cost. In the aforementioned context, the results yielding from clinical trials, which are testing the effectiveness of existing drugs and pharmaceutical formulas on diseases other than the ones they are currently treating, are closely dependent on the available data and the patients. The efficacy of such trials requires the pursuit of a number of aspects that need to be addressed ranging from the aggregation of data from various heterogeneous distributed sources (such as electronic health records - EHRs) to the intelligent processing of this data based on the clinical trial-specific requirements for choosing the appropriate patients eligible for recruitment. Within this framework, PONTE aims at providing a platform following a Service Oriented Architecture (SOA) approach that will offer intelligent automatic identification of individuals eligible (concerning their safety and clinical trial efficacy) to participate in clinical trials, as these will be designed and planned through a flexible authoring tool, enabling semantic interoperability of clinical care information systems with clinical research information systems and drug and disease knowledge databases, as well as the appliance of advanced data mining techniques and enhanced learning algorithms.

Related information

Open Access

Coordinator

CENTRE D'EXCELLENCE EN TECHNOLOGIES DE L'INFORMATION ET DE LA COMMUNICATION
Belgium

EU contribution: EUR 694 875


rue des frères wright 29
6041 Charleroi
Belgium
Administrative contact: Philippe Massonet
Tel.: +3271490799
Fax: +32 71 490799
E-mail

Participants

GOTTFRIED WILHELM LEIBNIZ UNIVERSITAET HANNOVER
Germany

EU contribution: EUR 119 379


Welfengarten
30167 HANNOVER
Germany
Administrative contact: Nikolaus Forgo
Tel.: +49 511 7628159
Fax: +49 511 7628290
E-mail
TECHNISCHE UNIVERSITAET DRESDEN
Germany

EU contribution: EUR 358 200


HELMHOLTZSTRASSE
01069 DRESDEN
Germany
Administrative contact: Sven Kreigenfeld
Tel.: +49 35146339744
Fax: +49 35146339742
E-mail
INSTITUTE OF COMMUNICATION AND COMPUTER SYSTEMS
Greece

EU contribution: EUR 568 800


Patission Str.
10682 ATHINA
Greece
Administrative contact: Yannis Vassiliou
Tel.: +30 210 7724374
Fax: +30 210 7722527
E-mail
NATIONAL AND KAPODISTRIAN UNIVERSITY OF ATHENS
Greece

EU contribution: EUR 139 200


CHRISTOU LADA
10561 ATHENS
Greece
Administrative contact: Efi Kafentzi
Tel.: +30 210 3689038
Fax: +30 210 3689008
E-mail
CONSIGLIO NAZIONALE DELLE RICERCHE
Italy

EU contribution: EUR 144 062


PIAZZALE ALDO MORO
00185 ROMA
Italy
Administrative contact: Giorgio Iervasi
Tel.: +39 050 3152017
Fax: +39 050 3152166
E-mail
LIETUVOS SVEIKATOS MOKSLU UNIVERSITETAS
Lithuania

EU contribution: EUR 0


A MICKEVICIAUS GATVE
44307 KAUNAS
Lithuania
Administrative contact: Robertas Bunevicius
Tel.: +370 460 30011
Fax: +370 460 30014
E-mail
Institute of Psychophysiology and Rehabilitation of the Kaunas University of Medicine
Participation ended
Lithuania

EU contribution: EUR 112 308


Vyduno
LT-00135 Palanga
Lithuania
Administrative contact: Robertas Bunevicius
Tel.: +370 460 30011
Fax: +370 460 30014
E-mail
KAUNO MEDICINOS UNIVERSITETAS
Participation ended
Lithuania

EU contribution: EUR 0


A MICKEVICIAUS G
3000 KAUNAS
Lithuania
Administrative contact: Robertas Bunevicius
Tel.: +370 460 30011
Fax: +370 460 30014
E-mail
STRATEGIC MEDICINE BV - SMI
Netherlands

EU contribution: EUR 137 400


JOHAN VAN OLDENBARNEVELTLAAN
2582NE DEN HAAG
Netherlands
Administrative contact: Michael Liebman
Tel.: +1 814 6595450
Fax: +1 814 4676334
E-mail
Cambridge University Hospitals NHS Foundation Trust
United Kingdom

EU contribution: EUR 220 800


Hills Rd
CB2 0QQ Cambridge
United Kingdom
Administrative contact: Stephen Kelleher
Tel.: +44 1223 217418
Fax: +44 1223 348494
E-mail
Record Number: 94150 / Last updated on: 2016-04-11