Objective
A number of epidemiological studies have consistently demonstrated the protective effects of fruits and vegetables with respect to several age related diseases. The aim of this project is to investigate the protective action of agents with potential use as functional food constituents with respect to cancer, diabetes and cardiovascular disease. In collaboration between EU and Indian research centers the proposal features a multipronged approach, where the protective action of various non-toxic agents are studied in vitro as well as in rodent models with respect to induction of DNA lesions, tumours and biomarkers for the development of diabetes, diabetic retinopathy and atherosclerosis. In addition, reduced availability of carcinogens and inhibition of their metabolic activation are investigated. Testing of the protective efficacy of functional food components in intervention cross-over studies in humans exposed to carcinogens, that are normally present at significant levels in the environment, represents an approach that has rarely been resorted to, and will be implemented under this project in Europe as well as in India using sophisticated molecular, cytogenetic and other analytical methods. Although there has been remarkable progress in our understanding of the processes that lead to neoplasia and diabetes, the mechanisms underlying chemoprevention are, in general, little understood. The results from this project are expected to provide an improved insight with respect to this topic.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- medical and health sciences clinical medicine cardiology cardiovascular diseases arteriosclerosis
- medical and health sciences clinical medicine endocrinology diabetes
- medical and health sciences clinical medicine oncology
- agricultural sciences agriculture, forestry, and fisheries agriculture horticulture vegetable growing
- medical and health sciences clinical medicine ophthalmology retinopathy
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP7-KBBE-2009-3
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
10691 Stockholm
Sweden
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.