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Content archived on 2024-06-18

DEVELOPMENT OF DIAMOND INTRACELLULAR NANOPROBES FOR ONCOGEN TRANSFORMATION DYNAMICS MONITORING IN LIVING CELLS

Objective

Dynamic information about biomolecular processes in living cells is important for fundamental understanding of cellular functions, which is one of the primary targets of molecular cell-biology with important applications to pharmacology. However fur further progress in this field, and this specifically for monitoring genomic processes, there is immense need for developing sensing and detection techniques that can operate with sufficient submicroscopic resolution inside the living cells and bringing real-time information about local biomolecular interactions. The present proposal makes a further, large step towards integration of forefront nanotechnology, chemistry and molecular biology expertise with a common goal of studying intracellular processes during the evolution steps of several types of frequently occurring cancers. This will create a novel tool studying the molecular processes in cells on nanoscale, which is the objective of this call. The aim of the DINAMO project is to develop the nanodiamond particle (NDP) non-invasive label-free nanotechnology platform for real-time monitoring (1) of living cells modified by oncogenic impact, (2) of the kinetics of gene-assisted processes in the cells. Based on the development work of DINAMO, we propose to apply to apply luminescent and single spin detection techniques for real-time dynamic monitoring of biomolecular processes in cells.

Fields of science (EuroSciVoc)

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Programme(s)

Multi-annual funding programmes that define the EU’s priorities for research and innovation.

Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

FP7-KBBE-2009-3
See other projects for this call

Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

CP-FP - Small or medium-scale focused research project

Coordinator

INTERUNIVERSITAIR MICRO-ELECTRONICA CENTRUM
EU contribution
€ 632 346,00
Address
KAPELDREEF 75
3001 Leuven
Belgium

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Region
Vlaams Gewest Prov. Vlaams-Brabant Arr. Leuven
Activity type
Research Organisations
Links
Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

No data

Participants (7)

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