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Content archived on 2024-06-18

Self-Replication in Dynamic Combinatorial Libraries

Objective

The host group has recently made a remarkable discovery: the spontaneous emergence of self-replicating molecules from a complex mixture of continuously interconverting peptide-derived compounds (dynamic combinatorial libraries). This project builds on this discovery and aims to come to a complete understanding of the mechanism of replication. Based on this understanding new replicators will then be developed. In the final stage the process of replication will be studied inside bilayer vesicles. If successful this will be the first example of a fully synthetic system that combines three important elements found in living systems: metabolism, replication and compartmentalization. Success of the project is critically dependent on combining the expertise of the host on dynamic combinatorial chemistry with the expertise of the researcher on the permeation of peptides through bilayer membranes.

Fields of science (EuroSciVoc)

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Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

FP7-PEOPLE-2009-IEF
See other projects for this call

Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

MC-IEF - Intra-European Fellowships (IEF)

Coordinator

RIJKSUNIVERSITEIT GRONINGEN
EU contribution
€ 169 035,20
Address
Broerstraat 5
9712CP Groningen
Netherlands

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Activity type
Higher or Secondary Education Establishments
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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

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