Objective
Endocrine disrupting chemicals (EDCs) are environmental contaminants which have the potential to disrupt the normal functioning of the neuroendocrine system in animals and so result in physiological dysfunction. The effects of EDCs on wildlife and their potential effects on human health are a major concern to the scientific community and public. In Europe, EDCs with estrogenic activity are prevalent in effluents from wastewater treatment works (WwTWs), and may result in feminization of male fish in downstream waters reducing their fertility. Most recently, studies have shown that WwTWs effluents contain high concentrations of antiandrogenic activity, but unlike estrogenic chemicals, the identity of the antiandrogenic contaminants is currently unknown. This project aims to identify the antiandrogenic contaminants in WwTWs effluents using passive sampling techniques to obtain an integrative extract of contaminated waters over time. Antiandrogens in effluent extracts will be identified by bioassay-directed fractionation using a combination of in vitro androgen receptor assays and mass spectrometry analyses. Once identified, the range of concentrations of key antiandrogenic chemicals in river waters will be determined using integrative passive sampling of sites upstream and downstream of effluent discharges. This project will provide a more informed knowledge of the range of EDCs in river waters. The work will contribute to environmental impact assessments of these new and emerging environmental chemicals and have importance in the regulation of discharges, and thus is of very wide interest to the government regulatory bodies, environment protection groups, industry and the wider public in Europe. The project will bring Dr Liscio to work with Dr Hill, and allow her to benefit from a number of scientific and complementary training activities which will prepare the fellow for an independent research career in environmental science.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
- medical and health sciences clinical medicine oncology prostate cancer
- engineering and technology environmental engineering water treatment processes wastewater treatment processes
- social sciences sociology demography fertility
- natural sciences earth and related environmental sciences environmental sciences pollution
- natural sciences chemical sciences analytical chemistry mass spectrometry
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP7-PEOPLE-2009-IEF
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
BN1 9RH Brighton
United Kingdom
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.