Reactive Oxygen Species and the Evolution of Life Histories

Projektinformationen

ROSELH

ID Finanzhilfevereinbarung: 252635

Abgeschlossenes Projekt

Startdatum 1 August 2010

Enddatum 13 Juni 2014

Finanziert unter

• Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013)

Gesamtkosten € 275 525,90

EU-Beitrag € 275 525,90

Koordiniert durch

MAX IV Laboratory, Lund University
Sweden

Ziel

The target of this proposal is ageing and its association with reproduction, immunity and behaviour. This is an area of biology that has intrigued every generation since Aristotle (c. 300 BC). We assess how free radicals (reactive oxygen species), so often identified as factors of ageing and immune disorders, exert selection on living organisms and whether resistance (and defence) towards free radicals may drive evolution of ageing in the wild. In particular, we study (i) how free radicals, the defence systems associated with them and the reproductive and the immune system interact to shape life history trade-offs, (ii) how free radicals impact on survival in the wild and, (iii) how epigenetic factors such as maternal hormones contribute to the formation of behavioural phenotypes (personalities) with different free radical profiles. This project integrates field studies and laboratory experiments using two uniquely suited model species (the Australian Painted dragon lizard and the zebra finch) and combines them with state-of-the-art molecular techniques to investigate variation in free radical production and defences. In spite of excellent work in the laboratory, this is one of the first attempts to study free radicals in the 'real world' and will extend Europe’s excellent reputation in evolutionary biology.

Wissenschaftliches Gebiet

• humanities › history and archaeology › history
• natural sciences › biological sciences › evolutionary biology
• medical and health sciences › basic medicine › immunology

Programm/Programme

• FP7-PEOPLE - Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013)

Thema/Themen

• FP7-PEOPLE-2009-IOF - Marie Curie Action: "International Outgoing Fellowships for Career Development"

Aufforderung zur Vorschlagseinreichung

FP7-PEOPLE-2009-IOF
Andere Projekte für diesen Aufruf anzeigen

Finanzierungsplan

MC-IOF - International Outgoing Fellowships (IOF)

Koordinator

MAX IV Laboratory, Lund University

Kontakt Verwaltung

Dennis Hasselquist (Prof.)

• EU-Beitrag: € 275 525,90
• Adresse: Paradisgatan 5c ; 22100 LUND ; Schweden
• Region: Södra Sverige › Sydsverige › Skåne län
• Aktivitätstyp: Higher or Secondary Education Establishments
• Gesamtkosten: Keine Daten