A role for the immunomodulatory capsular polysaccharide Sp1 expressed by Streptococcus pneumoniae in the treatment of Asthma

Project Information

SP1 AND ASTHMA

Grant agreement ID: 256378

Project closed

Start date 1 October 2010

End date 30 September 2014

Funded under

• Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013)

Total cost € 100 000,00

EU contribution € 100 000,00

Coordinated by

THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD, OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN
Ireland

Objective

This proposal will enable the candidate to successfully transition from a high profile US university to one of Europe’s leading universities, Trinity College Dublin (TCD), ranked 13th in Europe by the Times Higher Educational Supplement 2008. The candidate is poised to make major contributions to the Irish and EU research community by establishing her career at TCD. The candidate’s stellar research achievements and credibility as a scientist are evidenced by the fact that she has been awarded a prestigious career development award (CDA) from the Wellcome Trust, which will facilitate the move to Dublin. A Marie Curie IRG would significantly enhance the candidate’s career development within the EU over and above that achievable under the terms of the CDA. Specifically funding through this IRG alone would allow the candidate to a) grow and establish a research group at TCD by recruiting and training students b) continue a program of work in TCD that has already begun in Boston and can only be continued through funding from the IRG c) secure a long lasting collaboration with a high an internationally renowned scientist at Harvard Medical school, enhancing ties between this world famous institute and TCD d) diversify their research program by pursuing a project entirely distinct from that funded by the CDA. The proposed project represents an entirely novel approach for treatment of asthma by harnessing the immunomodulatory effects of a capsular polysaccharide molecule expressed by the airway commensal organism Streptococcus pneumoniae. It is predicted that Sp1 will induce immunomodulatory cytokines to protect against airway inflammation.

Fields of science (EuroSciVoc)

CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques.

• medical and health sciences › clinical medicine › pneumology › asthma
• natural sciences › biological sciences › biochemistry › biomolecules › carbohydrates

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Programme(s)

• FP7-PEOPLE - Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013)

Topic(s)

• FP7-PEOPLE-2009-RG - Marie Curie Action: "Reintegration Grants"

Call for proposal

FP7-PEOPLE-2009-RG
See other projects for this call

Funding Scheme

MC-IRG - International Re-integration Grants (IRG)

Coordinator

THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD, OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN

• EU contribution: € 100 000,00
• Address: COLLEGE GREEN TRINITY COLLEGE ; D02 CX56 Dublin ; Ireland
• Region: Ireland › Eastern and Midland › Dublin
• Activity type: Higher or Secondary Education Establishments
• Total cost: No data