Project description FET Open Show the project objective Hide the project objective The 2003 breakthrough discovery of a nanoscale optically active cation channel, channelrhodopsin-2, made it possible for the first time, to genetically re-engineer neuron cells to be photosensitive. It became possible to stimulate or inhibit individual action potentials at will, without further chemical modification. The capabilities have been demonstrated in a number of recent high profile journals detailing optical-neural control from cell culture to primate models. The light-gated cation channels were discovered and first applied by European researchers. The photonics and optoelectronics sectors, which can provide new stimulation technologies to this field, are additionally, European strengths. Nevertheless, in recent years, the dominant research output in this area has shifted to well-funded US laboratories.This proposal therefore aims to create a consortium to develop an array of ultra bright electronically controlled microLEDs which will provide a truly revolutionary tool for the neuroscience and neurotechnology community. The consortium consists of experts in the field who converge the many disciplines (optics, sophisticated LED fabrication, CMOS flip chip design and bonding, biophysics, molecular biology, neurophysiology) to bear on the complex, and crucial to neuroscience, problem of studying dendritic physiology and neural network dynamics. Advances in the techniques of this field will absolutely be required to further our understanding of brain function. The system we propose to develop will be powerful, sophisticated and at the same time, lead to a commercial spin-out that will provide them at relatively low cost. In the longer term, the tools we develop in this proposal will hasten our long term aims of developing an optogenetic retinal prosthesis. Fields of science natural sciencesbiological sciencesneurobiologynatural sciencesphysical scienceselectromagnetism and electronicsoptoelectronicsnatural sciencesbiological sciencesbiophysicsnatural sciencescomputer and information sciencesartificial intelligencecomputational intelligencenatural sciencesbiological sciencesmolecular biology Programme(s) FP7-ICT - Specific Programme "Cooperation": Information and communication technologies Topic(s) ICT-2009.8.0 - FET-Open: Challenging current thinking Call for proposal FP7-ICT-2009-C See other projects for this call Funding Scheme CP - Collaborative project (generic) Coordinator UNIVERSITY OF NEWCASTLE UPON TYNE EU contribution € 864 470,00 Address KINGS GATE NE1 7RU Newcastle Upon Tyne United Kingdom See on map Region North East (England) Northumberland and Tyne and Wear Tyneside Activity type Higher or Secondary Education Establishments Administrative Contact Christine Masterson (Dr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data Participants (6) Sort alphabetically Sort by EU Contribution Expand all Collapse all FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION Switzerland EU contribution € 0,00 Address MAULBEERSTRASSE 66 4058 Basel See on map Region Schweiz/Suisse/Svizzera Nordwestschweiz Basel-Stadt Activity type Research Organisations Administrative Contact Dorothy Searles (Ms.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data Novartis Forschungsstiftung Participation ended Switzerland EU contribution € 312 000,00 Address Maulbeerstrasse 66 4058 BASEL See on map Activity type Research Organisations Administrative Contact Dorothy Searles (Ms.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV Germany EU contribution € 309 600,00 Address HOFGARTENSTRASSE 8 80539 Munchen See on map Region Bayern Oberbayern München, Kreisfreie Stadt Activity type Research Organisations Administrative Contact Ernst Bamberg (Prof.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK Ireland EU contribution € 293 264,00 Address WESTERN ROAD T12 YN60 Cork See on map Region Ireland Southern South-East Activity type Higher or Secondary Education Establishments Administrative Contact Conor Delaney (Mr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data Scientifica Ltd United Kingdom EU contribution € 87 456,00 Address Kingfisher Court 1 TN22 1QQ Uckfield See on map Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact David Rogerson (Mr.) Links Contact the organisation Opens in new window Total cost No data IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE United Kingdom EU contribution € 323 210,00 Address SOUTH KENSINGTON CAMPUS EXHIBITION ROAD SW7 2AZ LONDON See on map Region London Inner London — West Westminster Activity type Higher or Secondary Education Establishments Administrative Contact Brooke Alasya (Ms.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data
