Objective
To identify the causal mechanisms leading to disease emergence, endemic maintenance and epidemic expansion,
epidemiologists would benefit tremendously from a full characterization of pathogen spread in space and time. The extensive
sequencing efforts for the ongoing swine-origin H1N1 influenza A epidemic testify that analyses of pathogen genetic data are
becoming increasingly important source of information in epidemiology. The new era of metagenomics promises to harvest
such data in unprecedented quantities with remarkable rapidity. With the objective to assist in designing effective intervention
and prevention strategies, we propose to develop a comprehensive statistical framework for uncovering the spatial and
temporal dynamics of pathogen genomes. To this aim, we will design and extend a series of computationally tractable models
that use the rapidly proliferating viral genome data to their full potential, connect molecular evolution to underlying spatial
processes, and pave the path to rigorous and powerful phylogeographic hypothesis testing approaches. Armed with these
tools, we will investigate how genetic variation within important viral pathogens, such as influenza, rabies and HIV, arises and
persists across a diverse range of hosts and environments.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
- medical and health sciences health sciences public health epidemiology
- natural sciences biological sciences genetics genomes viral genomes
- medical and health sciences health sciences infectious diseases RNA viruses influenza
- medical and health sciences health sciences infectious diseases RNA viruses HIV
- natural sciences biological sciences molecular biology molecular evolution
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
ERC-2010-StG_20091118
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Host institution
3000 Leuven
Belgium
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.