Objective
Breast cancer is the most common cause of death from cancer among European women, and over half of the worldwide breast cancer related mortalities occur in the developing world. Despite improvements in surgical techniques and chemoradiotherapy, the ability to cure patients with breast cancer remains limited and five year survival for patients with advanced disease is dismal. Expression profiling and biomarker discovery aims to provide means for tumour diagnosis, classification, and prediction of response to therapy and prognosis. This could potentially lead to the building of robust early detection modules, and personalised effective breast cancer therapies which would improve outcomes. The emerging field of proteomics targets the discovery of early stage biomarkers in biological tissue which could lead to new clinically valid biomarkers discovery.The goal of this application is to develop proteomic tests using different approaches for identification of breast cancer biomarkers which could ultimately form the basis of a screening and/or prognostication test. Using different biological samples and proteomic biomarkers’ discovery methods improves the prospects of classification and stratification of different biological groups. Early cancer detection, improved treatment selection and outcome are expected in return. This project is focused on early detection where comparative analysis of proteomes of normal individuals and patients with cancer, as well as different subgroups of patients, will be used to develop a “signature” of changes that are characteristic of breast cancer. Our study will be based on serum and breast tissue samples collected and analysed in 5 centres.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
- natural sciences biological sciences biochemistry biomolecules proteins proteomics
- social sciences sociology demography mortality
- medical and health sciences clinical medicine oncology breast cancer
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP7-PEOPLE-2009-IRSES
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
MC-IRSES - International research staff exchange scheme (IRSES)
Coordinator
SO17 1BJ SOUTHAMPTON
United Kingdom
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.