Objective The EUCOMMTOOLS Collaborative Project responds to the topic ‘HEALTH.2010.2.1.1-1: Large-scale efforts in mouse functional genomics to determine the functions of genes and their involvement in disease.’ EUCOMMTOOLS will provide, in a systematic high-throughput way, genetic tools and resources contributing to the determination of every gene’s function in any cell type of the entire organism at any given point in time.To contribute to the IKMC goals, EUCOMMTOOLS will establish 250 BAC-CreERT2 transgenic mice allowing inducible conditional gene inactivation in most cell types of the organism at any given point in time. Furthermore, EUCOMMTOOLS will establish 3.500 additional, conditionally targeted mouse ES cells to complete the IKMC resource. In addition, various important technological developments will valorise the EUCOMMTOOLS resources: a genetic toolkit for multipurpose usage of the conditional knockout alleles, and improvements of the Cre-recombinase function. The EUCOMMTOOLS Cre transgenic resource as well as its library of conditionally mutated mouse ES cells enables the establishment of mutant mice world-wide in a standardized, cost-effective and time-saving manner, making mouse mutants more easily available to the wider biomedical research community than possible previously. All EUCOMMTOOLS vectors, mutant ES cells and mice will be displayed via the EUCOMMTOOLS web portal and will be distributed by EuMMCR and EMMA to the scientific community.In general, EUCOMMTOOLS fosters existing European consortia which address mouse functional genomics, mouse mutant phenotyping, and mouse archiving.Taken together, EUCOMMTOOLS will further advance the functional annotation of the entire mouse genome and thereby enhance the understanding of the molecular basis of disease. Furthermore, it will support drug development by SMEs and the pharmaceutical industry. Fields of science medical and health sciencesbasic medicinepharmacology and pharmacydrug discoverynatural sciencesbiological sciencesgeneticsgenomes Programme(s) FP7-HEALTH - Specific Programme "Cooperation": Health Topic(s) HEALTH.2010.2.1.1-1 - Large-scale efforts in mouse functional genomics to determine the functions of genes and their involvement in disease. FP7-HEALTH-2010-single-stage Call for proposal FP7-HEALTH-2010-single-stage See other projects for this call Funding Scheme CP-IP - Large-scale integrating project Coordinator HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH EU contribution € 4 717 398,55 Address INGOLSTADTER LANDSTRASSE 1 85764 Neuherberg Germany See on map Region Bayern Oberbayern München, Landkreis Activity type Research Organisations Administrative Contact Jürgen Ertel (Dr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data Participants (10) Sort alphabetically Sort by EU Contribution Expand all Collapse all GENOME RESEARCH LIMITED United Kingdom EU contribution € 4 743 667,00 Address WELLCOME SANGER INSTITUTE WELLCOME GENOME CAMPUS HINXTON CB10 1SA SAFFRON WALDEN See on map Region East of England East Anglia Cambridgeshire CC Activity type Research Organisations Administrative Contact Derek Matthews (Dr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data EUROPEAN MOLECULAR BIOLOGY LABORATORY Germany EU contribution € 278 800,93 Address Meyerhofstrasse 1 69117 Heidelberg See on map Region Baden-Württemberg Karlsruhe Heidelberg, Stadtkreis Activity type Research Organisations Administrative Contact Phil Irving (Dr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data TECHNISCHE UNIVERSITAET DRESDEN Germany EU contribution € 568 800,00 Address HELMHOLTZSTRASSE 10 01069 Dresden See on map Region Sachsen Dresden Dresden, Kreisfreie Stadt Activity type Higher or Secondary Education Establishments Administrative Contact Sven Kreigenfeld (Mr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data CONSIGLIO NAZIONALE DELLE RICERCHE Italy EU contribution € 359 604,00 Address PIAZZALE ALDO MORO 7 00185 Roma See on map Region Centro (IT) Lazio Roma Activity type Research Organisations Administrative Contact Assunta Vesce (Ms.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data CENTRE EUROPEEN DE RECHERCHE EN BIOLOGIE ET MEDECINE France EU contribution € 360 000,00 Address Rue Laurent Fries 1 67404 Illkirch Graffenstaden See on map Region Grand Est Alsace Bas-Rhin Activity type Research Organisations Administrative Contact Steve Brooks (Dr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data UNIVERSIDAD MIGUEL HERNANDEZ DE ELCHE Participation ended Spain EU contribution € 589 165,25 Address AVENIDA DE LA UNIVERSIDAD S-N 03202 Elche See on map Region Este Comunitat Valenciana Alicante/Alacant Activity type Higher or Secondary Education Establishments Administrative Contact Rafael Gandía- Balaguer (Mr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data MEDICAL RESEARCH COUNCIL United Kingdom EU contribution No data Address 20 Park Crescent W1B 1AL LONDON See on map Activity type Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) Administrative Contact Hilary Gates (Dr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data UNIVERSIDAD DE MURCIA Spain EU contribution € 160 038,20 Address AVENIDA TENIENTE FLOMESTA S/N - EDIFICIO CONVALECENCIA 30003 Murcia See on map Region Sur Región de Murcia Murcia Activity type Higher or Secondary Education Establishments Administrative Contact Maria Sánchez-Merenciano Juárez (Ms.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data MONASH UNIVERSITY Australia EU contribution € 222 199,07 Address Wellington Road 3800 Victoria See on map Activity type Higher or Secondary Education Establishments Administrative Contact Silvio Tiziani Links Contact the organisation Opens in new window Website Opens in new window Total cost No data THE JACKSON LABORATORY NON PROFIT CORPORATION United States EU contribution No data Address MAIN STREET 610 04609 Bar Harbor See on map Activity type Other Administrative Contact Stephen Murray (Dr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data