Novel medical adsorbents for extracorporeal treatment of life threatening conditions

Projektinformationen

MEAD-ET

ID Finanzhilfevereinbarung: 247547

Abgeschlossenes Projekt

Startdatum 1 Dezember 2010

Enddatum 30 November 2014

Finanziert unter

• Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013)

Gesamtkosten € 113 400,00

EU-Beitrag € 113 400,00

Koordiniert durch

UNIVERSITY OF BRIGHTON
United Kingdom

Ziel

Recently a program of development of super active carbonic adsorbents for the deep purification of whole blood and blood plasma was realised in the series of joint projects between The EU partners and Ukraine. As a result, nanostructured activated carbons with mass-fractal internal structure and unique capacity towards tightly protein-bound toxins, uncoated or coated with albumin conformers have been synthesized. These materials have been tested and approved for clinical use in Ukraine and Uzbekistan expressly for the treatment of severe hepatic insufficiency, renal insufficiency and multi-organ failure. The goal of this project is the transfer of these findings to a new version of nanostructured carbon, synthesized on the base of phenol-formaldehyde resin modified and coated with haemocompatible dextrans and its sulfated derivates in the Department of Physico-Chemical Mechanisms of Adsorptive Detoxification in the Institute of Experimental Pathology, Oncology and Radiobiology Nat. Acad. of Sci of Ukraine and studied in the School of Pharmacy and Biomolecular Sciences at the University of Brighton (biocompatibility, inflammatory mediator adsorption) and the Laboratory of Immunology, School of Medicine and Pharmacy, University of Clermont-Ferrand (investigation of immunoadsorptive properties of nanostructured carbonic adsorbents coated with sulfated polysaccharides). This program gives the opportunity to cultivate a high scientific quality consortium consisting of 2 European and 1 third country academic institute, with the aim to sustain and create new collaborative partnerships between EU partners and Ukraine, and transfer knowledge and technologies in one of the most exciting fields of modern biomaterial science. Focusing on the development of extracorporeal methods for toxin removal, for the treatment of many life threatening conditions and chronic conditions, that result in a low quality of patient life.

Wissenschaftliches Gebiet

• medical and health sciences › basic medicine › immunology
• natural sciences › biological sciences › biochemistry › biomolecules › carbohydrates
• medical and health sciences › clinical medicine › oncology
• medical and health sciences › basic medicine › pathology
• medical and health sciences › basic medicine › pharmacology and pharmacy

Programm/Programme

• FP7-PEOPLE - Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013)

Thema/Themen

• FP7-PEOPLE-2009-IRSES - Marie Curie Action "International Research Staff Exchange Scheme"

Aufforderung zur Vorschlagseinreichung

FP7-PEOPLE-2009-IRSES
Andere Projekte für diesen Aufruf anzeigen

Finanzierungsplan

MC-IRSES - International research staff exchange scheme (IRSES)

Koordinator

UNIVERSITY OF BRIGHTON

Kontakt Verwaltung

Carol Angela Howell (Dr.)

• EU-Beitrag: € 63 000,00
• Adresse: LEWES ROAD MITHRAS HOUSE ; BN2 4AT Brighton ; Vereinigtes Königreich
• Region: South East (England) › Surrey, East and West Sussex › Brighton and Hove
• Aktivitätstyp: Higher or Secondary Education Establishments
• Gesamtkosten: Keine Daten

Beteiligte (1)

UNIVERSITE D'AUVERGNE CLERMONT-FERRAND 1

Frankreich

Kontakt Verwaltung

Arlette Tridon (Dr.)

• EU-Beitrag: € 50 400,00
• Adresse: BOULEVARD FRANCOIS MITTERAND 49 ; 63001 Clermont-Ferrand
• Aktivitätstyp: Higher or Secondary Education Establishments
• Gesamtkosten: Keine Daten