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MySPINE

Project ID: 269909
Funded under

Functional prognosis simulation of patient-specific spinal treatment for clinical use

From 2011-03-01 to 2014-08-31, closed project | MySPINE Website

Project details

Total cost:

EUR 3 935 335

EU contribution:

EUR 3 038 000

Coordinated in:

Spain

Call for proposal:

FP7-ICT-2009-6See other projects for this call

Funding scheme:

CP - Collaborative project (generic)

Description

Improving the treatment of lower back pain

The MySpine project aims to improve the treatment of lower back pain. Nowadays treatment and prognosis of spinal disc degeneration are still based on trial and error decisions from the surgeon, leading to numerous post treatment complications and eventual morbidity. MySpine is working on a rational engineering approach based on advanced ICT and predictive systems that are patient-specific.

The main outputs of the project are the creation of a prototype computing platform with a graphical user interface for clinical settings and a patient-specific database of the lumbar spine. This interface will give clinicians the ability to virtually explore patient-specific treatment outcomes of disc degeneration, from short-term biomechanical ending to long-term mechanobiological tissue evolution.

The MySpine project (<a href="http://www.myspineproject.eu">www.myspineproject.eu</a>) covers part of the "Virtual Physiological Human" (VPH), which deals with biomedical modelling and simulation of the human body. 

 

Objective

Treatment and prognosis of spinal disc degeneration are still based on trial and error clinical decisions from the surgeon leading to numerous post treatment complications and eventual morbidity. A rational engineering approach based on advanced ICT and patient-specific predictive systems to treat various spinal pathologies needs to be developed to guide clinicians and improve long-term clinical outcomes. In silico virtual assessment of the evolution of treatments for patient-specific lumbar spine geometries, tissue properties, and loading histories is the cornerstone of such predictive system. Focus must be made on functional patient-specific models that have mechanobiological predictive capabilities. The objective of My SPINE is to adapt and integrate existing generic finite element (FE) models and use them as ICT tools in a clinical setting. The predictive system will consist in a set of specialized computing platforms. A geometrical and mechanical patient-specific model will be built, involving specialized processes such as image segmentation and analysis, mesh morphing, FE simulations, and optimizations. Based on the analysis of each integrated biomechanical and mechanobiological model, results will be evaluated in a probabilistic way, helping clinician to safely assess the risks and benefits of each simulated treatment. The main outputs of the project are the creation of a prototype computing platform with a graphical user interface for clinical settings and a patient-specific database of the lumbar spine. This interface will give clinicians the ability to virtually explore patient-specific treatment outcomes of disc degeneration, from short-term biomechanical ending to long-term mechanobiological tissue evolution. The project will impact ehealth by bringing new engineering rationale in the clinical decision-process. Impact is thus directly linked to ICT companies for clinical software development and hospital for the development of new clinical protocols.

Coordinator

FUNDACIO INSTITUT DE BIOENGINYERIA DE CATALUNYA
Spain

EU contribution: EUR 484 663


CARRER BALDIRI REIXAC PLANTA 2A 10-12
08028 BARCELONA
Spain
Activity type: Research Organisations
Administrative contact: Josep Samitier
Tel.: +34 93 403 11 45
Fax: +34 934 020 439

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Participants

TECHNISCHE UNIVERSITAET WIEN
Austria

EU contribution: EUR 344 110


KARLSPLATZ 13
1040 WIEN
Austria
Activity type: Higher or Secondary Education Establishments
Administrative contact: Christian Hellmich
Tel.: +43 1 58801 20220
Fax: +43 1 58801 920220

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UNIVERSIDAD POMPEU FABRA
Participation ended
Spain

EU contribution: EUR 179 343


PLACA DE LA MERCE, 10-12
08002 BARCELONA
Spain
Activity type: Higher or Secondary Education Establishments
Administrative contact: Eva Martín
Tel.: +34 93 542 21 40
Fax: +34 93 542 20 02

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CETIR CENTRE MEDIC SL
Spain

EU contribution: EUR 326 110


Calle Londres 6
08029 Barcelona
Spain
Activity type: Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative contact: Albert Madrigal
Tel.: +34 935035414
Fax: +34 934736078

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CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
France

EU contribution: EUR 266 886


RUE MICHEL ANGE 3
75794 PARIS
France
Activity type: Research Organisations
Administrative contact: Bénedicte SAMYN
Tel.: +33 3 20 12 58 07
Fax: +33 3 20 63 00 43

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BUDAI EGESZSEGKOZPONT KFT
Hungary

EU contribution: EUR 296 782


NAGY JENO UTCA 8
1126 BUDAPEST
Hungary
Activity type: Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative contact: Péter Pál Varga
Tel.: +3618877988
Fax: +3618877987

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TECHNISCHE UNIVERSITEIT EINDHOVEN
Netherlands

EU contribution: EUR 497 953


GROENE LOPER 5
5612 EINDHOVEN
Netherlands
Activity type: Higher or Secondary Education Establishments
Administrative contact: Rob DEBEIJ
Tel.: +31 40 247 5132
Fax: +31 40 247 2206

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THE UNIVERSITY OF SHEFFIELD
United Kingdom

EU contribution: EUR 531 866


FIRTH COURT WESTERN BANK
S10 2TN SHEFFIELD
United Kingdom
Activity type: Higher or Secondary Education Establishments
Administrative contact: Joanne Watson
Tel.: +44 114 222 4754
Fax: +44 114 222 1452

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UNIVERSITE DE TECHNOLOGIE DE COMPIEGNE
France

EU contribution: EUR 110 287


Centre Benjamin Franklin, Rue Roger Couttolenc
60206 COMPIEGNE
France
Activity type: Higher or Secondary Education Establishments
Administrative contact: Marie Christine Ho Ba Tho
Tel.: +33 3 44 23 49 18
Fax: +33 3 44 23 46 74

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Subjects

Life Sciences
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