Project description
Virtual Physiological Human
Inflammatory Bowel diseases (IBDs) constitute on of the largest healthcare problems in the Western World, affecting over 1 million European citizens alone, 700,000 of whom suffer from Crohn's disease.Grading of Crohn's disease severity is important to determine treatment strategy and to quantify the response to treatment. Colonoscopy in combination with the assessment of biopsy samples is considered the reference standard for diagnosis of all IBD. However, the procedure is invasive and requires extensive bowel preparation, which is considered very burdensome by most patients. Moreover, it only gives information on superficial abnormalities.The VIGOR++ project aims to create a multiscale, personalised GI tract model, which facilitates improved detection of Crohn's disease and drives an accurate index of Crohn's disease severity.VIGOR++ will acquire laboratory, MRI, colonoscopy and microscopy (histopathology) data in order to develop the targeted ICT tools. A novel integration of existing models is employed to predict features on the molecular to cellular scale (microscopy/colonoscopy) from descriptive properties at the organ to patient scales (MRI/laboratory). Effectively, this would render the standard methods (colonoscopy/biopsy) superfluous.The tools sustain early diagnosis, improved therapy planning and a better quality of life for patients. The clinical benefit is demonstrated by an assessment of the tools' performance to predict Crohn's disease status. Moreover, a preliminary study will be performed in which the effect of therapy is evaluated using the VIGOR++ tools.The consortium harbours leading groups in abdominal radiology, medical image analysis, modelling, scientific visualization, gastroenterology and commercial diffusion. Importantly, it has solid plans for the commercialisation of the generated innovations. Notably, the ICT tools are developed in a clinically used environment, 3Dnet™ Suite, so that they can be readily commercialized.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
- medical and health sciences clinical medicine gastroenterology inflammatory bowel disease
- natural sciences physical sciences optics microscopy
- medical and health sciences clinical medicine radiology
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP7-ICT-2009-6
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
2628 CN DELFT
Netherlands
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.