Objectif International child health programmes in low-income countries are justified in term of their impact on child survival. However, the effect estimates are usually calculated from performance indicators and assumptions about efficacy based on small-scale target-specific studies. There is little follow-up of how the programmes are implemented in real life.This approach is clearly not sufficient. Recent studies have consistently shown that vaccines and micronutrients have non-specific effects, i.e. effects which are not explained by prevention of the targeted infections or deficiencies. These effects are often sex-differential. Furthermore, interventions may interact. Hence, the overall impact of child health programs can not be extrapolated from small-scale target-specific studies. There is a need to assess the real life impact and cost-effectiveness of child health intervention programmes in the context where they are being used.We propose to use health and demographic surveillance system (HDSS) sites in Africa to register information routinely on all interventions in childhood, such as all vaccinations, micronutrient supplementation, and de-worming, given at health centres or in campaigns. Using this information we will measure the overall health impact of the child health programs.The HDSS platform can also be used for testing modifications of the current health programmes. We will test a recent finding from a randomised trial in Guinea-Bissau: providing early measles vaccine at 4.5 and 9 months of age compared with the recommended measles vaccine at age 9 months reduced overall mortality from 4.5 to 36 months of age by astonishing 49%.The HDSS sites already collect data on mortality, and mortality would be the main outcome, but we also aim to identify other relevant comparable outcome parameters which correlate with mortality and which can be used to assess the overall impact of existing and new interventions. Champ scientifique social sciencessociologydemographymortalitymedical and health sciencesbasic medicinepharmacology and pharmacypharmaceutical drugsvaccines Programme(s) FP7-HEALTH - Specific Programme "Cooperation": Health Thème(s) HEALTH.2010.3.4-6 - Impact and cost-effectiveness of existing major health programmes. FP7-HEALTH-2010-single-stage Appel à propositions FP7-HEALTH-2010-single-stage Voir d’autres projets de cet appel Régime de financement CP-FP-SICA - Small/medium-scale focused research project for specific cooperation actions dedicated to international cooperation partner countries(SICA) Coordinateur STATENS SERUM INSTITUT Contribution de l’UE € 347 280,00 Adresse ARTILLERIVEJ 5 2300 Kobenhavn S Danemark Voir sur la carte Région Danmark Hovedstaden Byen København Type d’activité Research Organisations Contact administratif Torben Theilmann (Mr.) Liens Contacter l’organisation Opens in new window Site web Opens in new window Coût total Aucune donnée Participants (7) Trier par ordre alphabétique Trier par contribution de l’UE Tout développer Tout réduire INSTITUTO NACIONAL DE SAUDE PUBLICA Guinée-Bissau Contribution de l’UE € 929 390,00 Adresse Av. Combatente da Liberdade da Patria 100 1004 Bissau Codex Voir sur la carte Type d’activité Research Organisations Contact administratif Amabelia Rodrigues (Mrs.) Liens Contacter l’organisation Opens in new window Site web Opens in new window Coût total Aucune donnée CENTRE DE RECHERCHE EN SANTE DE NOUNA Burkina Contribution de l’UE € 928 400,00 Adresse BP 02 13 Nouna Voir sur la carte Type d’activité Research Organisations Contact administratif Ali Sie (Dr.) Liens Contacter l’organisation Opens in new window Coût total Aucune donnée GHANA HEALTH SERVICE Ghana Contribution de l’UE € 495 300,00 Adresse CATHERDRAL SQUARE ADABRAKA NA ACCRA Voir sur la carte Type d’activité Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) Contact administratif Abraham Hodgson (Dr.) Liens Contacter l’organisation Opens in new window Coût total Aucune donnée UNIVERSITATSKLINIKUM HEIDELBERG Allemagne Contribution de l’UE € 215 000,00 Adresse IM NEUENHEIMER FELD 672 69120 Heidelberg Voir sur la carte Région Baden-Württemberg Karlsruhe Heidelberg, Stadtkreis Type d’activité Higher or Secondary Education Establishments Contact administratif Maria Schmitt (Ms.) Liens Contacter l’organisation Opens in new window Site web Opens in new window Coût total Aucune donnée MEDICAL RESEARCH COUNCIL Participation terminée Royaume-Uni Contribution de l’UE Aucune donnée Adresse 20 Park Crescent W1B 1AL LONDON Voir sur la carte Type d’activité Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) Contact administratif Katie Louise Flanagan (Dr.) Liens Contacter l’organisation Opens in new window Site web Opens in new window Coût total Aucune donnée INDEPTH NETWORK Ghana Contribution de l’UE € 39 600,00 Adresse Mensah Wood Street, East Legon 11 KD ACCRA Voir sur la carte Type d’activité Other Contact administratif Osman Sankoh (Dr.) Liens Contacter l’organisation Opens in new window Site web Opens in new window Coût total Aucune donnée RIJKSINSTITUUT VOOR VOLKSGEZONDHEID EN MILIEU Pays-Bas Contribution de l’UE € 45 000,00 Adresse Antonie Van Leeuwenhoeklaan 9 3721 MA Bilthoven Voir sur la carte Région West-Nederland Utrecht Utrecht Type d’activité Research Organisations Contact administratif Rob Riesmeijer (Mr.) Liens Contacter l’organisation Opens in new window Site web Opens in new window Coût total Aucune donnée