Objectif Over fifteen percent of the western population suffer from osteoarthritis. For severe disability, total joint replacement remains the onlty treatment. The ageing population is growing and their expectations for an active, high quality lifestyle is increasing. The number of knee joint replacements is predicted to increase five time by 2025. While technology for knee joint replacements has advanced considerably over the last decade, knee joint replacements do yet restore the natural function or provide the longevity expected for a population expecting - fifty more active years after fifty. An alternative is needed.We wil address the potential of regenerative biological scaffolds to re-engineer and regenerate the knee in early stage degenerative disease. We will build upon our successful research and clinical trials in the application of regenerative biological scaffolds in the cardiovascular system.. We will research and develop bioprocesses to produce a portfolio of tissue specific regenerative biological scaffolds to replace disrupted and degenerative tissues in the knee, including ligaments, meniscus, bone and cartilage. and evaluate their biomechanical, biotribological and biological function. We will investigate the regenerative potential of these novel biological scaffolds individually and collectively in the knee as a bioengineering system.This research will open the opportunity for a paradigm shift for treatment of degenerative disease in the knee and offer the potential for substantially delaying the need for a joint replacement in hundreds of thousands of patients every year. Programme(s) FP7-IDEAS-ERC - Specific programme: "Ideas" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013) Thème(s) ERC-AG-PE8 - ERC Advanced Grant - Products and process engineering Appel à propositions ERC-2010-AdG_20100224 Voir d’autres projets de cet appel Régime de financement ERC-AG - ERC Advanced Grant Institution d’accueil UNIVERSITY OF LEEDS Contribution de l’UE € 2 495 134,30 Adresse WOODHOUSE LANE LS2 9JT Leeds Royaume-Uni Voir sur la carte Région Yorkshire and the Humber West Yorkshire Leeds Type d’activité Higher or Secondary Education Establishments Contact administratif Benjamin Williams (Mr.) Chercheur principal John Fisher (Prof.) Liens Contacter l’organisation Opens in new window Site web Opens in new window Coût total Aucune donnée Bénéficiaires (1) Trier par ordre alphabétique Trier par contribution de l’UE Tout développer Tout réduire UNIVERSITY OF LEEDS Royaume-Uni Contribution de l’UE € 2 495 134,30 Adresse WOODHOUSE LANE LS2 9JT Leeds Voir sur la carte Région Yorkshire and the Humber West Yorkshire Leeds Type d’activité Higher or Secondary Education Establishments Contact administratif Benjamin Williams (Mr.) Chercheur principal John Fisher (Prof.) Liens Contacter l’organisation Opens in new window Site web Opens in new window Coût total Aucune donnée
